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12/29/2006 Brain Protein Pathway May Be a Key to Parkinson's Disease
A protein called HIPK2 is essential for the survival of dopamine neurons, according to an
MJFF-funded study in mice. The results suggest that the molecular pathway in which the protein functions could be a possible new target for therapy, the study authors say.
12/21/2006 Study Suggests Association between High Body Mass Index and Increased Parkinson's Risk
The results of a study published in the December issue of Neurology suggest an association between high body mass index (BMI) and an increased risk of Parkinson's disease in middle-age women and men.
12/19/2006 Low LDL Level Linked to Parkinson's Disease
People with low levels of LDL cholesterol -- bad cholesterol -- are more likely to have Parkinson's disease than those with high levels, a U.S. study finds.
12/18/2006 New Jersey Moves on Embryonic Stem Cell Work
State officials announced plans Monday to invest $7 million next year in federally restricted embryonic stem cell research and $3 million for less controversial research into adult stem cells.
12/14/2006 Parkinson's and Gambling: Is It the Drugs or the Disease?
Doctors and researchers continue to puzzle over why certain people taking medication for Parkinson's disease begin to display compulsive behaviors.
12/12/2006 Possible Fingerprint of Alzheimer's Found
12/08/2006 Accepting the Risk in Hopes of a Cure
In a partnership with The Michael J. Fox Foundation, San Diego biotech Ceregene Inc. initiates the Phase II trial of CERE-120, a novel gene therapy product that has shown potential in preclinical trials to slow or stop the progression of Parkinson's disease.
12/06/2006 Avicena Enters Parkinson's Drug Supply Agreement
Biotechnology company Avicena Group has signed an agreement with the National Institute of Neurological Disorders and Stroke to supply PD-02, its Parkinson's disease drug candidate, for a phase III trial.
11/27/2006 Parkinson's May Lower Driving Safety
People with Parkinson's disease are especially prone to making driving mistakes if they're distracted while behind the wheel, a U.S. study finds.
11/26/2006 No Exaggeration: Parkinson's Offers Lessons
The Westchester edition of Sunday's New York Times featured a column on David Eger, founder of Music for Parkinson's Research, one of largest community fundraisers that benefits The Michael J. Fox Foundation.
11/26/2006 Pilates Exercises May Help People with Parkinson's
The Parkinson Center of the Oregon Health and Science University in Portland held a Pilates pilot program earlier this year, and improvement was seen in participants' rigidity and balance.
11/23/2006 Ties between Cholesterol and Parkinson's in Women
Women with higher levels of total cholesterol appear to be at decreased risk for developing Parkinson's disease, according to a report by researchers in the Netherlands.
11/22/2006 Parkinson's Gene Reveals Its Secrets
Scientists say they've discovered how a mutation on the LRRK2 gene damages the brain.
11/20/2006 Schwarz Pharma's Neupro to Get Approval for Treatment of Parkinson's Disease
Parkinson's disease throughout all 25 European Union countries. Neupro is already approved and on the market in Europe as monotherapy for the treatment of patients with early-stage PD.
10/27/2006 Symptoms of Parkinson's Disease and Common Side Effects of Parkinson's Medications
Recent news reports may have resulted in some confusion about the difference between symptoms of Parkinson’s disease and side effects of the medications used to treat it, as well as the reasons why Parkinson’s symptoms manifest differently in different patients and at different times.
10/19/2006 Parkinson's Drug May Raise Risk of Valve Trouble
Periodic heart valve testing is "essential" when cabergoline or pergolide is used at a high dose.
10/19/2006 Clinical Study Focuses on Depression in Patients with Parkinson's
A 19-site placebo-controlled study is the first to test the antidepressant medications paroxetine (brand name Paxil) and venlafaxine (brand name Effexor) in patients with Parkinson’s.
10/18/2006 Synchronous Neuronal Firing May Underlie Parkinson's Disease
In a finding that contradicts current theories behind Parkinson's disease, neuroscientists at Duke University Medical Center have discovered in mice that critical nerve cells fire all at the same time and thus overwhelm the brain's ability to control the body's movements.
10/17/2006 Gene Therapy Trials Show Promise against Parkinson's
Two Phase I safety studies of human gene therapy for Parkinson's disease have shown that the technique is safe and may reduce symptoms for patients.
10/12/2006 Foundation Launches Parkinson's Genetics Database PDGene
The Michael J. Fox Foundation announced that it has created PDGene (
www.pdgene.org), an online inventory of studies on genes implicated in Parkinson’s disease.
10/10/2006 Dopamine Plays Critical Role in Sleep
The brain chemical dopamine plays an important role in regulating sleep and brain activity associated with dreaming, a Duke University Medical Center study finds.
10/05/2006 Plans Unveiled for State-financed Stem Cell Work in California
The California Institute for Regenerative Medicine says it will spend $823 million on basic stem cell research, $899 million on applied or preclinical research and $656 million on taking new treatments through clinical trials.
09/28/2006 Breakthrough Offers New Tool For Studying Degenerative Disease
Scientists have discovered a new technique to let them watch, visualize and precisely measure a key oxidant in animal cells, an important breakthrough that could dramatically speed research on degnerative disease.
09/26/2006 Laser Probe of a Brain Pigment's Anatomy May Offer Insight into Parkinson's Disease
In a finding that may offer clues about Parkinson's disease, a team led by Duke University researchers used a sophisticated laser system to gain evidence that a dark brown pigment that accumulates in people's brains consists of layers of two other pigments commonly found in hair.
09/26/2006 Paul Allen's
It took only three years for a Seattle lab founded by Microsoft mogul and philanthropist Paul Allen to revolutionize the landscape of neuroscience by creating a map of the brain that goes far beyond topography to pinpoint the workings of individual cells.
09/25/2006 Clinical Trial News: Gathering Data on Parkinson's Patients in Their Homes
A group of doctors is testing the feasibility of gathering data on patients in their own homes.
09/21/2006 Canadian Doctors Hail Azilect in Treatment of Parkinson's
Some doctors are calling Azilect, recently approved by Health Canada, the most significant drug for the treatment of Parkinson's disease in four decades.
09/19/2006 In Science-based Medicine, Where Does Luck Fit In?
Considering that luck plays a role in our health has become anathema in an era of evidence-based medicine.
09/19/2006 PlayStation's Serious Side: Fighting Disease
Working with Stanford University's
Folding@home distributed computing project, Sony has harnessed the PlayStation 3's technology to help study how proteins sometimes form incorrectly in the human body -- with results linked to diseases including Parkinson's and Alzheimer's.
09/18/2006 Researchers Grow Neural, Blood Vessel Cells from Adult Stem Cells
Scientists have predicted that embryonic stem cells might lead to cures for various diseases and conditions such as heart disease, Parkinson’s or spinal cord injuries. Now, researchers have isolated adult stem cells from blood that can be directed to turn into five types of cells, including bone, blood vessel and nerve cells.
09/14/2006 Pesticide Exposure Could Increase Risk of Early Onset Parkinson's Disease
Researchers at Emory University and the Georgia Institute of Technology report that low-level exposure to a banned but lingering pesticide appears to accelerate changes in the brain that can potentially lead to the onset of Parkinson's disease symptoms.
09/12/2006 A Way to Slow Parkinson's?
In work funded by The Michael J. Fox Foundation, Texas researchers report that blocking a specific form of a brain chemical slows brain cell loss in an animal model of Parkinson's disease.
09/11/2006 Having Two Copies of G2019S Parkinson's Gene Mutation Doesn't Lead to More Severe Disease
A group of Parkinson's disease researchers concluded there are no observable differences between those who have two copies of the most common mutation of the recently discovered LRRK2 gene and those who have only one copy.
09/11/2006 Two Firms to Collaborate on Development of Phase II Product for Dyskinesia in Parkinson's Disease
A Swiss pharmaceutical company and a Finnish biotechnology company announced a strategic collaboration to advance the development of fipamezole (JP-1730) for the treatment of dyskinesia in people with Parkinson’s.
09/10/2006 Armin Meyer, 92, U.S. Ambassador to Three Countries, Is Dead
Armin H. Meyer, a former United States ambassador to Lebanon, Iran and Japan, died August 13 in Washington. He was 92. The cause was Parkinson’s disease, said his daughter.
09/05/2006 Neupro® (Rotigotine Transdermal) Patch Offers Additional Benefits
At the 10th Congress of the European Federation of Neurological Societies (EFNS), new data from clinical trials with the Neupro® (rotigotine transdermal) Patch indicated additional benefits for patients with early and advanced Parkinson's disease.
09/05/2006 Novel Mechanism Of Manganese-induced Neurological Dysfunction Discovered
Researchers from the Johns Hopkins Bloomberg School of Public Health and Thomas Jefferson University have discovered a potential explanation to why Parkinson's-like symptoms may occur with manganese exposure.
09/04/2006 Harvard Scientists Report Key Stem Cell Research Findings
Scientists at Harvard University have identified key compounds that stimulate stem cell growth in the brain.
08/31/2006 Research into Early Warning Test for Parkinson's Receives National Recognition in Australia
Researchers at Australia's National Health and Medical Research Council have developed a new blood test to provide early detection for the loss of neuromelanin -- a pigment that disappears in the brains of people with Parkinson's -- which may predict the onset of PD.
08/30/2006 Deep Brain Stimulation Effective for Parkinson's
A new study finds that deep brain stimulation is more effective for patients with advanced disease than medication and that it may have fewer side effects than drugs do.
08/29/2006 Melvin Schwartz, Nobel Laureate in Physics, Dies at 73
Melvin Schwartz, a Nobel Prize-winning physicist and former Stanford professor who founded his own pioneering Internet company in Silicon Valley, died Monday in Twin Falls, Idaho, after a long struggle with Parkinson's disease. He was 73.
08/24/2006 In New Method for Stem Cells, Viable Embryos
Biologists have developed a technique for establishing colonies of human embryonic stem cells from an early human embryo without destroying it.
08/22/2006 Teva's Azilect Gets Health Canada Approval for Parkinson's Disease
Teva Pharmaceutical Industries Ltd. announced that Azilect (rasagiline tablets), the first once-daily oral treatment for Parkinson's disease, has been approved by Health Canada. The drug is expected to become available in Canada this September.
08/21/2006 Snail Toxin May Spur New Drugs For Alzheimer's, Parkinson's, Depression
A newly discovered toxin in a snail species' venom could be a useful tool in designing new medicines for brain disorders including Alzheimer's, Parkinson's, depression, nicotine addiction and perhaps schizophrenia.
08/16/2006 Prehistoric Plant Intrigues New York Parkinson's Researchers
A scientist at The New York Botanical Garden in the Bronx is studying cycads, plants dating to the days of dinosaurs that may hold the key to the human brain malfunctions that trigger the tremors, slowness and poor balance associated with Parkinson's.
08/15/2006 Some Scientists See Shift in Stem Cell Hopes
In the five years since President Bush authorized and at the same time restricted research on human embryonic stem cells, a marked shift has taken place in some scientists’ views of how the research is likely to benefit medicine.
08/11/2006 TIVO Alert!
Tune in to CNBC's "On The Money" on Friday, August 11th at 7 pm EST. The Foundation's Chairman of the Board, David Golub, and Board member David Einhorn, will discuss Einhorn's success at the World Series of Poker and his generous donation to the Foundation.
08/11/2006 Nicotine Slows Parkinson's Disease
A new study in monkeys suggests the drug may help if given early.
08/08/2006 Link between Parkinson's and Allergic Rhinitis Revealed
People with Parkinson's disease are three times more likely than non-sufferers to have been troubled by allergic rhinitis – an inflammatory nasal response to pollen or other airborne particles – a new study finds.
08/08/2006 Strong Evidence of a Genetic Risk Factor for Parkinson's Disease
A Mayo Clinic-led international research collaboration supported by The Michael J. Fox Foundation's
Edmond J. Safra Global Genetics Consortia provides strong evidence that a genetic risk factor may account for 3 percent of the cause of Parkinson's disease.
08/08/2006 The Foundation Thanks David Einhorn for Donating His Winnings From the World Series of Poker
08/04/2006 Nanoparticles Take a Direct Route to Brain, U.S. Study Shows
Researchers examining nanoparticles from manganese oxide (prevalent in welding fumes) have shown that when breathed in, the particles quickly follow an efficient path from the nose to several brain regions.
08/01/2006 Vitamin B6 May Cut Risk of Parkinson's Disease
A new study published in the July 2006 issue of the journal Neurology suggests that a higher dietary intake of vitamin B6 may decrease the risk of Parkinson's disease.
07/28/2006 New Genetic Model for Parkinson's Disease
Researchers at the Karolinska Institute in Sweden have mimicked in mice disturbances of mitochondria thought to be one cause of Parkinson's disease.
07/25/2006 Poll: Majority of Public Disapprove of Bush's Stem Cell Veto
A majority of Americans disapprove of President Bush's veto of a bill expanding federal funding for embryonic stem cell research, though they say they believe he did so on principle, a USA TODAY/Gallup Poll shows.
07/19/2006 First Bush Veto Maintains Limits on Stem Cell Use
President Bush readied the first veto of his presidency Wednesday to stop legislation easing limits on federal funding for embryonic stem-cell research.
07/19/2006 Ask the House to Override the Presidential Veto -- Call Your Representative Now!
The House of Representatives will bring up H.R. 810 as early as this afternoon (Wednesday, July 19) in an attempt to override the President's veto. That override must pass the House by a 2/3 majority, so your help is needed now more than ever to activate overwhelming support.
07/19/2006 In First Veto, Bush Stops Stem Cell Bill
President Bush readied the first veto of his presidency Wednesday to stop legislation easing limits on federal funding for embryonic stem-cell research.
07/19/2006 Run Like a Fox on November 5, 2006
The Michael J. Fox Foundation is honored to be a part of the ING New York City Marathon's expanded charity program. Team Fox has a limited number of guaranteed entries available for this year's race.
07/18/2006 Senate Passes Stem Cell Bill, Defying Veto Threat
After two days of debate the Senate voted to expand federal funding of embryonic stem cell research, sending the measure to President Bush for a promised veto, the first of his presidency.
07/12/2006 The LRRK2-G2019S Mutation: Opening a Novel Era in Parkinson's Disease Genetics
The role of genetic factors in the etiology of Parkinson's disease has long been considered negligible, but a series of recent discoveries are dramatically changing this view.
07/11/2006 Patients With Rare Diseases Work to Jump-Start Research
Nonprofits and small patient-founded groups are playing an increasing role in establishing and managing biospecimen banks required for drug development for rare or underfunded diseases.
07/07/2006 H. pylori Eradication Improves Levodopa Absorption
Eradicating H. pylori infection improves levodopa pharmacokinetics and increases "on-time" in patients with motor fluctuations, according to a new double-blind study.
06/30/2006 CBS to re-broadcast
On March 13 (9:00pm ET/PT) CBS aired "Saving Milly," a made-for-TV movie based on the bestselling book and real-life journey of political journalist and MJFF Board member Mort Kondracke.
06/30/2006 Senate to Consider Stem Cell Proposals
Senate leaders from both parties agreed yesterday to schedule a vote on a package of bills that would loosen President Bush's five-year-old restrictions on human embryonic stem cell research.
06/28/2006 Exelon Cleared by U.S. FDA for Parkinson's Disease Dementia
The U.S. Food and Drug Administration has approved Exelon for the treatment of mild to moderate Parkinson's disease dementia.
06/26/2006 Pesticide Exposure Associated With Parkinson's Disease
The first large-scale, prospective study to examine possible links between chronic, low-dose exposure to pesticides and Parkinson's disease has shown that individuals reporting exposure to pesticides had a 70 percent higher incidence of PD than those not reporting exposure.
06/23/2006 Merck Drops Parkinson's Drug After Studies Fail
German pharmaceutical firm Merck KGaA abandoned the development of Sarizotan, an experimental medicine for Parkinson's disease, after disappointing studies.
06/23/2006 Protecting Neurons from Parkinson's Disease
Researchers have uncovered a way to protect neurons from degeneration and death in animal models of Parkinson'?s disease.
06/15/2006 Zelapar Approved to Significantly Reduce
The U.S. Food and Drug Administration approved Zelapar(R), a once-daily adjunct therapy for Parkinson's disease patients being treated with levodopa/carbidopa who exhibit deterioration in the quality of their response to this therapy.
06/14/2006 New Pan-European Survey Reveals
Over 80 percent of people with Parkinson's disease suffer from depressive symptoms as part of their condition, according to a pan-European survey released today, but there is a "disconnect" when it comes to talking about these symptoms with their doctors.
06/14/2006 Pesticide Use Ups Parkinson's Risk in Men
A new Mayo Clinic telephone survey has found that men exposed to pesticides run a higher risk of developing Parkinson's disease.
04/16/2006 Read Michael J. Fox's Inspiring Interview with DATELINE
DATELINE(NBC) recently featured an hour-long program dedicated to Parkinson's disease. During the show, Katie Couric interviewed Michael J. Fox and discussed the role he and the Foundation play in the fight against the disease.
02/22/2006 Michael J. Fox's Welcoming Remarks at Inaugural World Parkinson Congress
Michael J. Fox delivered inspiring welcoming remarks to an audience of over 2,000 at the inaugural World Parkinson Congress in Washington, DC.
