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  • Experimental capture of miRNA targetomes: disease-specific 3′UTR library-based miRNA targetomics for Parkinson’s disease
    2024
    RESTRICTED
    Title: Experimental capture of miRNA targetomes: disease-specific 3′UTR library-based miRNA targetomics for Parkinson’s disease
    Author(s): Martin Hart, Fabian Kern, Claudia Fecher‐Trost, Lena Krammes, Ernesto Aparicio, Annika Engel, Pascal Hirsch, Viktoria Wagner, Verena Keller, Georges Pierre Schmartz, Stefanie Rheinheimer, Caroline Diener, Ulrike Fischer, Jens Mayer, Markus R. Meyer, Veit Flockerzi, Andreas Keller, Eckart Meese
    Journal Name: Experimental & Molecular Medicine
    Publisher: Springer Science and Business Media LLC
    Vol: 56
    Issue #: 4
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s12276-024-01202-5
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    Citation Count: 0
  • Genetic and multi‐omic risk assessment of Alzheimer's disease implicates core associated biological domains
    2024
    RESTRICTED
    Title: Genetic and multi‐omic risk assessment of Alzheimer's disease implicates core associated biological domains
    Author(s): Gregory A. Cary, Jesse C. Wiley, Jake Gockley, S. Keegan, Sai Sruthi Amirtha Ganesh, Laura M Heath, Robert R. Butler, Lara M. Mangravite, Benjamin A. Logsdon, Frank M. Longo, Aĺlan I. Levey, Anna K. Greenwood, Gregory W. Carter
    Journal Name: Alzheimer's & Dementia: Translational Research & Clinical Interventions
    Publisher: Wiley
    Vol: 10
    Issue #: 2
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.1002/trc2.12461
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    Citation Count: 0
  • Mitochondrial DNA deletions in the cerebrospinal fluid of patients with idiopathic REM sleep behaviour disorder
    2024
    RESTRICTED
    Title: Mitochondrial DNA deletions in the cerebrospinal fluid of patients with idiopathic REM sleep behaviour disorder
    Author(s): Margalida Puigròs, Anna Calderon, Daniel Martín-Ruiz, Mónica Serradell, Manel Fernández, Amaia Muñoz‐Lopetegi, Gerard Mayà, Joan Santamaría, Carles Gaig, Anna Colell, Eduard Tolosa, Álex Iranzo, Ramón Trullás
    Journal Name: eBioMedicine
    Publisher: Elsevier BV
    Vol: 102
    Issue #:
    Start Page: 105065
    End Page: 105065
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.1016/j.ebiom.2024.105065
    Best OA location URL: http://www.thelancet.com/article/S2352396424001002/pdf
    Citation Count: 0
  • Peripheral neuronal activation shapes the microbiome and alters gut physiology
    2024
    RESTRICTED
    Title: Peripheral neuronal activation shapes the microbiome and alters gut physiology
    Author(s): Jessica Griffiths, Byung Hoon Yoo, Peter Thuy-Boun, Victor Cantu, Kelly C. Weldon, Collin Challis, Michael J. Sweredoski, Ken Y. Chan, Taren Thron, Gil Sharon, Annie Moradian, Gregory Humphrey, Qing Zhu, Justin P. Shaffer, Dennis W. Wolan, Pieter C. Dorrestein, Rob Knight, Viviana Gradinaru, Sarkis K. Mazmanian
    Journal Name: Cell Reports
    Publisher: Elsevier BV
    Vol: 43
    Issue #: 4
    Start Page: 113953
    End Page: 113953
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by, cc-by
    DOI - Digital Object Identifier: 10.1016/j.celrep.2024.113953
    Best OA location URL: http://www.cell.com/article/S221112472400281X/pdf
    Citation Count: 0
  • Prasinezumab slows motor progression in rapidly progressing early-stage Parkinson’s disease
    2024
    RESTRICTED
    Title: Prasinezumab slows motor progression in rapidly progressing early-stage Parkinson’s disease
    Author(s): Gennaro Pagano, Kirsten I. Taylor, Judith Cabrera, Tanya Simuni, Kenneth Marek, Ronald B. Postuma, Nicola Pavese, Fabrizio Stocchi, Kathrin Brockmann, Hanno Svoboda, Dylan Trundell, Annabelle Monnet, Rachelle S. Doody, Paulo Fontoura, Geoffrey A. Kerchner, Patrik Brundin, Tania Nikolcheva, Azad Bonni
    Journal Name: Nature Medicine
    Publisher: Springer Science and Business Media LLC
    Vol: 30
    Issue #: 4
    Start Page: 1096
    End Page: 1103
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41591-024-02886-y
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    Citation Count: 0
  • The integrated stress response pathway and neuromodulator signaling in the brain: lessons learned from dystonia
    2024
    RESTRICTED
    Title: The integrated stress response pathway and neuromodulator signaling in the brain: lessons learned from dystonia
    Author(s): Nicole Calakos, Zachary F. Caffall
    Journal Name: Journal of Clinical Investigation
    Publisher: American Society for Clinical Investigation
    Vol: 134
    Issue #: 7
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by, cc-by
    DOI - Digital Object Identifier: 10.1172/jci177833
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    Citation Count: 0
  • Investigating the aspect of asymmetry in brain-first versus body-first Parkinson’s disease
    2024
    RESTRICTED
    Title: Investigating the aspect of asymmetry in brain-first versus body-first Parkinson’s disease
    Author(s): Sofie Lövdal, Giulia Carli, Beatrice Orso, Michael Biehl, Dario Arnaldi, Pietro Mattioli, Annette Janzen, Elisabeth Sittig, Silvia Morbelli, Jan Booij, Wolfgang H. Oertel, Klaus L. Leenders, Sanne K. Meles
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Vol: 10
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41531-024-00685-3
    Best OA location URL: https://www.nature.com/articles/s41531-024-00685-3.pdf
    Citation Count: 0
  • Genotype–phenotype correlation in PRKN-associated Parkinson’s disease
    2024
    RESTRICTED
    Title: Genotype–phenotype correlation in PRKN-associated Parkinson’s disease
    Author(s): Poornima Jayadev Menon, Sara Sambin, Baptiste Criniere-Boizet, Thomas Courtin, Christelle Tesson, Fanny Casse, Melanie Ferrien, Louise‐Laure Mariani, Stéphanie Carvalho, François‐Xavier Lejeune, Sana Rebbah, Gaspard Martet, Marion Houot, Aymeric Lanore, Graziella Mangone, Elise Roze, Marie Vidailhet, Jan Aasly, Ziv Gan‐Or, Eric Yu, Yves Dauvilliers, Alexander Zimprich, Volker Tomantschger, Walter Pirker, Ignacio Álvarez, Pau Pástor, Alessio Di Fonzo, Kailash P. Bhatia, Francesca Magrinelli, Henry Houlden, Raquel Real, Andrea Quattrone, Patricia Limousin, Prasad Korlipara, Tom Foltynie, Donald Grosset, N. M. Williams, Derek P. Narendra, Hsin-Pin Lin, Čarna Jovanović, Marina Svetel, Timothy Lynch, Amy Gallagher, Wim Vandenberghe, Thomas Gasser, Kathrin Brockmann, Huw R. Morris, Max Borsche, Christine Klein, Olga Corti, Alexis Brice, Suzanne Lesage, Jean‐Christophe Corvol
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Vol: 10
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41531-024-00677-3
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    Citation Count: 0
  • Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue
    2024
    RESTRICTED
    Title: Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue
    Author(s): Dhruva Dhavale, Alexander M. Barclay, Collin G. Borcik, Katherine Basore, Deborah A. Berthold, Isabelle R. Gordon, Jialu Liu, Moses H. Milchberg, Jennifer Y. O’Shea, Michaël Rau, Zachary Smith, Shamik Sen, Brock Summers, John W. Smith, Owen Warmuth, Richard J. Perrin, Joel S. Perlmutter, Qian Chen, James A.J. Fitzpatrick, Charles D. Schwieters, Emad Tajkhorshid, Chad M. Rienstra, Paul T. Kotzbauer
    Journal Name: Nature Communications
    Publisher: Springer Science and Business Media LLC
    Vol: 15
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41467-024-46832-5
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    Citation Count: 0
  • Development and characterization of a non-human primate model of disseminated synucleinopathy
    2024
    RESTRICTED
    Title: Development and characterization of a non-human primate model of disseminated synucleinopathy
    Author(s): Alberto J. Rico, Almudena Corcho, Julia Chocarro, Goiaz Ariznabarreta, Elvira Roda, Adriana Honrubia, Patricia Arnáiz, José L. Lanciego
    Journal Name: Frontiers in Neuroanatomy
    Publisher: Frontiers Media SA
    Vol: 18
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by, cc-by
    DOI - Digital Object Identifier: 10.3389/fnana.2024.1355940
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    Citation Count: 0
  • Development of quantitative high-throughput screening assays to identify, validate, and optimize small-molecule stabilizers of misfolded β-glucocerebrosidase with therapeutic potential for Gaucher disease and Parkinson's disease
    2024
    RESTRICTED
    Title: Development of quantitative high-throughput screening assays to identify, validate, and optimize small-molecule stabilizers of misfolded β-glucocerebrosidase with therapeutic potential for Gaucher disease and Parkinson's disease
    Author(s):
    Journal Name:
    Publisher: Cold Spring Harbor Laboratory
    Vol:
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1101/2024.03.22.586364
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    Citation Count:
  • Lysosomal storage disease proteo/lipidomic profiling using nMOST links ferritinophagy with mitochondrial iron deficiencies in cells lacking NPC2
    2024
    RESTRICTED
    Title: Lysosomal storage disease proteo/lipidomic profiling using nMOST links ferritinophagy with mitochondrial iron deficiencies in cells lacking NPC2
    Author(s):
    Journal Name:
    Publisher: Cold Spring Harbor Laboratory
    Vol:
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1101/2024.03.26.586828
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    Citation Count:
  • Single-cell multiplex chromatin and RNA interactions in ageing human brain
    2024
    RESTRICTED
    Title: Single-cell multiplex chromatin and RNA interactions in ageing human brain
    Author(s): Xingzhao Wen, Zhifei Luo, Wenming Zhao, Riccardo Calandrelli, Tri C. Nguyen, Xueyi Wan, John Lalith Charles Richard, Sheng Zhong
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Vol: 628
    Issue #: 8008
    Start Page: 648
    End Page: 656
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41586-024-07239-w
    Best OA location URL: https://www.nature.com/articles/s41586-024-07239-w.pdf
    Citation Count: 1
  • TREM1 disrupts myeloid bioenergetics and cognitive function in aging and Alzheimer disease mouse models
    2024
    RESTRICTED
    Title: TREM1 disrupts myeloid bioenergetics and cognitive function in aging and Alzheimer disease mouse models
    Author(s): Edward N. Wilson, Congcong Wang, Michelle S. Swarovski, Kristy A Zera, Hannah Ennerfelt, Qian Wang, Aisling M. Chaney, Esha Gauba, Javier A. Ramos Benitez, Yann Le Guen, Paras Minhas, Maharshi Panchal, Yuting Tan, Eran Blacher, Chinyere Agbaegbu Iweka, Haley C. Cropper, Poorva Jain, Qingkun Liu, Swapnil S. Mehta, Abigail J. Zuckerman, Matthew Xin, Jacob Umans, Jie Huang, Aarooran Sivakumaran Durairaj, Geidy E. Serrano, Thomas G. Beach, Michael D. Greicius, Michelle L. James, Marion S. Buckwalter, Melanie R. McReynolds, Joshua D. Rabinowitz, Katrin I. Andreasson
    Journal Name: Nature Neuroscience
    Publisher: Springer Science and Business Media LLC
    Vol: 27
    Issue #: 5
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1038/s41593-024-01610-w
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    Citation Count: 0
  • Spatial transcriptomics reveals molecular dysfunction associated with cortical Lewy pathology
    2024
    RESTRICTED
    Title: Spatial transcriptomics reveals molecular dysfunction associated with cortical Lewy pathology
    Author(s): Thomas J. Goralski, Lindsay Meyerdirk, Libby Breton, L. Brasseur, Kevin Kurgat, Daniella DeWeerd, Lisa Turner, Katelyn Becker, Marie Adams, Daniel J. Newhouse, Michael X. Henderson
    Journal Name: Nature Communications
    Publisher: Springer Science and Business Media LLC
    Vol: 15
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by, cc-by
    DOI - Digital Object Identifier: 10.1038/s41467-024-47027-8
    Best OA location URL: https://www.nature.com/articles/s41467-024-47027-8.pdf
    Citation Count: 1
  • The oligogenic structure of amyotrophic lateral sclerosis has genetic testing, counselling, and therapeutic implications
    2024
    RESTRICTED
    Title: The oligogenic structure of amyotrophic lateral sclerosis has genetic testing, counselling, and therapeutic implications
    Author(s):
    Journal Name:
    Publisher: Cold Spring Harbor Laboratory
    Vol:
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
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    DOI - Digital Object Identifier: 10.1101/2024.03.21.24304693
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    Citation Count:
  • [3H]-NFPS binding to the glycine transporter 1 in the hemi-parkinsonian rat brain
    2024
    RESTRICTED
    Title: [3H]-NFPS binding to the glycine transporter 1 in the hemi-parkinsonian rat brain
    Author(s): Imane Frouni, Esther Kim, Judy Shaqfah, Dominique Bédard, Cynthia Kwan, Sébastien Belliveau, Philippe Huot
    Journal Name: Experimental Brain Research
    Publisher: Springer Science and Business Media LLC
    Vol: 242
    Issue #: 5
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by
    DOI - Digital Object Identifier: 10.1007/s00221-024-06815-w
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    Citation Count: 0
  • Biochemical Fractionation of Human α-Synuclein in a Drosophila Model of Synucleinopathies
    2024
    RESTRICTED
    Title: Biochemical Fractionation of Human α-Synuclein in a Drosophila Model of Synucleinopathies
    Author(s): Khondamir Imomnazarov, Joshua Lopez‐Scarim, Ila Bagheri, Valerie Joers, Malú G. Tansey, Alfonso Martín-Peña
    Journal Name: International Journal of Molecular Sciences
    Publisher: MDPI AG
    Vol: 25
    Issue #: 7
    Start Page: 3643
    End Page: 3643
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by, cc-by
    DOI - Digital Object Identifier: 10.3390/ijms25073643
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    Citation Count: 0
  • Parkinson’s Disease is Predominantly a Genetic Disease
    2024
    RESTRICTED
    Title: Parkinson’s Disease is Predominantly a Genetic Disease
    Author(s): Shen‐Yang Lim, Christine Klein
    Journal Name: Journal of Parkinson's Disease
    Publisher: IOS Press
    Vol: 14
    Issue #: 3
    Start Page: 1
    End Page: 16
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.3233/jpd-230376
    Best OA location URL:
    Citation Count: 1
  • Regulatory SVA retrotransposons and classical HLA genotyped-transcripts associated with Parkinson’s disease
    2024
    RESTRICTED
    Title: Regulatory SVA retrotransposons and classical HLA genotyped-transcripts associated with Parkinson’s disease
    Author(s): Jerzy K. Kulski, Shingo Suzuki, Takashi Shiina, Abigail L Pfaff, Sulev Kõks
    Journal Name: Frontiers in Immunology
    Publisher: Frontiers Media SA
    Vol: 15
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by
    DOI - Digital Object Identifier: 10.3389/fimmu.2024.1349030
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    Citation Count: 0
  • RAB3 phosphorylation by pathogenic LRRK2 impairs trafficking of synaptic vesicle precursors
    2024
    RESTRICTED
    Title: RAB3 phosphorylation by pathogenic LRRK2 impairs trafficking of synaptic vesicle precursors
    Author(s): Dan Dou, Jayne Aiken, Erika L.F. Holzbaur
    Journal Name: Journal of Cell Biology
    Publisher: Rockefeller University Press
    Vol: 223
    Issue #: 6
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by, cc-by
    DOI - Digital Object Identifier: 10.1083/jcb.202307092
    Best OA location URL:
    Citation Count: 1
  • Profiling Protein–Protein Interactions in the Human Brain by Refined Cofractionation Mass Spectrometry
    2024
    RESTRICTED
    Title: Profiling Protein–Protein Interactions in the Human Brain by Refined Cofractionation Mass Spectrometry
    Author(s): Him K. Shrestha, Dong Geun Lee, Zhiping Wu, Z Y Wang, Yingxue Fu, Xusheng Wang, Geidy E. Serrano, Thomas G. Beach, Junmin Peng
    Journal Name: Journal of Proteome Research
    Publisher: American Chemical Society (ACS)
    Vol: 23
    Issue #: 4
    Start Page: 1221
    End Page: 1231
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1021/acs.jproteome.3c00685
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    Citation Count: 0
  • A topographical atlas of α-synuclein dosage and cell type-specific expression in adult mouse brain and peripheral organs
    2024
    RESTRICTED
    Title: A topographical atlas of α-synuclein dosage and cell type-specific expression in adult mouse brain and peripheral organs
    Author(s): Haley Geertsma, Zoe Fisk, Lillian Sauline, Alice Prigent, Kevin Kurgat, Steve Callaghan, Benjamin R. Arenkiel, Brit Mollenhauer, Michael G. Schlossmacher, Christine Stadelmann, Julianna J. Tomlinson, Michael X. Henderson, Maxime W.C. Rousseaux
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Vol: 10
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by, cc-by
    DOI - Digital Object Identifier: 10.1038/s41531-024-00672-8
    Best OA location URL:
    Citation Count: 0
  • AccessPD as a next generation registry to accelerate Parkinson’s disease research
    2024
    RESTRICTED
    Title: AccessPD as a next generation registry to accelerate Parkinson’s disease research
    Author(s): Yun-Hsuan Chang, María Teresa Periñán, Matt Wilson, Alastair Noyce
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Vol: 10
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by
    DOI - Digital Object Identifier: 10.1038/s41531-024-00651-z
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    Citation Count: 0
  • In Silico Investigation of Parkin-Activating Mutations Using Simulations and Network Modeling
    2024
    RESTRICTED
    Title: In Silico Investigation of Parkin-Activating Mutations Using Simulations and Network Modeling
    Author(s): Naeyma N. Islam, Caleb A. Weber, Matt Coban, Liam T. Cocker, Fabienne C. Fiesel, Wolfdieter Springer, Thomas R. Caulfield
    Journal Name: Biomolecules
    Publisher: MDPI AG
    Vol: 14
    Issue #: 3
    Start Page: 365
    End Page: 365
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by
    DOI - Digital Object Identifier: 10.3390/biom14030365
    Best OA location URL:
    Citation Count: 0
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