The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Community Fast Track, 2004Gene Transfer of Pleiotrophin to Aged Parkinsonian Pre-Clinical Models
Parkinson's disease involves the death of a specific population of neurons in the brain that supply the neurotransmitter dopamine (DA). A group of molecules termed neurotrophic factors have been...
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Community Fast Track, 2004Maintenance of Nerve Terminals by Local Synthesis of Proteins in Axons
Function of the nervous system depends on maintaining the connections between neurons throughout life. Loss of these synaptic connections is thought to be one of the early events in neurodegenerative...
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Community Fast Track, 2004Dysregulation of Ubiquitylation in Parkinson's Disease
It is now widely accepted that the ability to maintain appropriate levels of proteins is of fundamental importance to the normal function of neurons and other cells. The levels of many proteins are...
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Community Fast Track, 2004Cytoprotective role of ABAD in Parkinson disease
Mitochondrial dysfunction and loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) are the features of Parkinson's disease (PD). We have identified a multifunctional member of the...
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Community Fast Track, 2004Alpha-synuclein and Environmental Exposures: A Study in Humans
The long-term goal of this research is to find the cause or causes of typical, late-onset sporadic Parkinson's disease (PD). To date the search for genetically determined risk factors that could...
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Cell Replacement Therapy, 2004Novel protocols for the differentiation and functional integration of embryonic and neural stem cell-derived dopaminergic neurons in rodent models ofParkinson’s Disease
The properties of stem cells have created the exciting possibility of producing high numbers of virtually any human cell type for cell replacement therapies. However, their implementation in Parkinson...
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Our funding programs support basic, translational and clinical research from academia and industry.