The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Rapid Response Innovation Awards, 2011A New Strategy to Ameliorate Chemically-induced Parkinson-like Symptoms by Engaging the Spinal Locomotor Circuitry with Epidural Stimulation
Objective/Rationale:
Our objective is to determine if we can change the level of excitability of the spinal cord circuitry that controls posture and locomotion so that the sensory information derived... -
Research Grant, 2011Effect of Novel Neuronal Nicotinic Receptor Compounds on Treatment of Levodopa-induced Dyskinesia in Parkinson's Disease
Promising Outcomes of Original Grant:
The aim of the original grant was to identify compounds specifically targeting one or more neuronal nicotinic receptors (NNRs) in the central nervous system for... -
LRRK2 Cohort Working Group, 2011Gait and Motor Symptoms in Healthy Asymptomatic Relatives of Patients with PD Who Are Carriers of Mutations in the LRRK2 Gene
Objective/Rationale:
Gait disturbances play a major role in the motor manifestation of Parkinson's disease (PD). We aim to explore the possibility that subtle gait alterations are also present in the... -
LRRK2 Challenge, 2011Regulation of LRRK2 Activity by Nitric Oxide-Mediated Protein S-Nitrosylation
Objective/Rationale:
Mutations in the LRRK2 gene are a common cause of familial Parkinson’s disease (PD). Familial mutations can influence the GTPase or kinase activity of LRRK2 which may be... -
MJFF Research Grant, 2011In Vivo Validation of the AAV-alpha-synuclein Vectors Generated by UNC for Distribution to MJFF Supported Research Community
Objective/Rationale:
The Michael J. Fox Foundation would like to generate those tools and reagents that can be of greatest use to PD researchers. Working with Dr. R. Jude Samulski at The University... -
MJFF Research Grant, 2011Nmnat Function in Axonal Neuroprotection
Promising Outcomes of Original Grant:
In the previous application, we tested the hypothesis that gene delivery of NMNAT-1 would protect striatal innervation in 6-OHDA lesioned pre-clinical models and...
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Our funding programs support basic, translational and clinical research from academia and industry.