The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant Supplement, 2020Measuring LRRK2-Mediated Rab Protein in Parkinson’s Disease
Study Rationale:
The discovery of LRRK2 (Leucine rich repeat kinase 2) recently as a gene that causes Parkinson’s disease has provided considerable insights into the development of both familial and... -
Research Grant Supplement, 2020Discovery of Selective PET Imaging Agents for Tauopathies and Alpha-Synuclein
Study Rationale:
The development of alpha-synuclein and tau imaging agents will be valuable for people with Parkinson’s disease and Frontal Temporal Dementia (FTD), as deposits of these proteins... -
Biosample Use Program, 2020Mass Spectrometric Analysis of Glucocerebrosidase Protein Levels and Spinal Fluid in People with Parkinson’s
Study Rationale:
Mutations in the glucocerebrosidase (GBA) gene are among the most important risk factors for developing Parkinson´s disease. GBA activity is reduced in cerebrospinal fluid (CSF) of... -
Biosample Use Program, 2020Adaptive Immune Markers for Predicting Cognitive Decline in Parkinson’s Disease
Study Rationale:
For reasons not well understood, people with Parkinson's disease are at risk for developing dementia, a decline in memory, thinking and/or language abilities severe enough to... -
Research Grant, 2020Cytokine Production by Adaptive Immune Cells in Parkinson’s Disease: Response to Diverse Biological Stimuli
Study Rationale:
Many studies indicate a role for the adaptive immune system in Parkinson’s disease. Our study will produce proteins called cytokines that play a role in the immune response to... -
Research Grant, 2020Targeted and Untargeted Mass Spectrometry-Based Proteome Investigation of Urine in Parkinson’s Disease
Study Rationale:
There is an urgent need for disease indicators — also known as biomarkers — in Parkinson’s disease to enable early diagnoses and treatment response monitoring. Urine is a promising...
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Our funding programs support basic, translational and clinical research from academia and industry.