The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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MJFF Research Grant, 2008Validation of Neuroimaging Biomarkers for Nigrostriatal Neurons
Objective/Rationale:
No treatment has been proven to slow progression of Parkinson's disease. To develop such a treatment requires an objective measure of disease progression. Current clinically based... -
Therapeutics Development Initiative, 2008Selective Inhibition of Cyclic Nucleotide Phosphodiesterase Type 7 (PDE7): A Novel and Efficacious Approach to Treating Parkinson's Disease
Objective/Rationale:
Levodopa is the gold standard treatment for Parkinson’s disease. However, its continued use results in serious side effects including abnormal involuntary movements, or... -
Therapeutics Development Initiative, 2008Development of ERb agonists for the treatment of Parkinson's Disease
Objective/Rationale:
Estrogens modulate many cerebral functions such as mental state, mood, cognition and locomotion. Data indicate that estrogens may slow down the development and progression of PD... -
Therapeutics Development Initiative, 2008Multiphosphatase Inhibitors as PD Therapeutics
Objective/Rationale:
Parkinson’s disease has multiple genetic and environmental causes. As a result, therapeutic efforts aimed at a single cause of the disease may have limited value. ShanaRx has... -
MJFF Research Grant, 2008Development of Lewy Bodies MRI Imaging Agents for the Early Diagnosis of Parkinson's Disease and Related Disorders
Promising Outcomes of Original Grant:
Parkinson’s disease and related conditions are the most common movement disorders. Pathological studies reveal abundant protein deposits in the affected neurons... -
Rapid Response Innovation Awards, 2008In Vivo Assessment of Alpha-Synuclein Secretion
Objective/Rationale:
The pathophysiological roles of the secreted AS forms remain largely unknown. We have identified oligomeric and monomeric AS species in the conditioned medium (CM) of SHSY5Y cells...
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Our funding programs support basic, translational and clinical research from academia and industry.