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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Rapid Response Innovation Awards, 2007
    Gene-Environment Interactions in Parkinson's Disease

    Objective/Rationale:
    Although the causes of sporadic Parkinson’s disease are still unknown, recent evidence suggests that exposure to pesticides increases the risk for PD. However, most of these...

  • Rapid Response Innovation Awards, 2007
    Everyday Action Impairment in People with Parkinson's Disease Dementia/Dementia with Lewy Bodies

    Objective/Rationale:
    Parkinson’s disease (PD) and Parkinson’s Disease Dementia/Dementia with Lewy Bodies (PDD/DLB) have been associated with cognitive deficits and everyday action impairment (EAI; e.g...

  • Rapid Response Innovation Awards, 2007
    Ethics of Sham Surgery Controls to Test Novel Parkinson's Disease Interventions

    Objective/Rationale: 
    When experimental treatments involve neurosurgery, researchers often use a placebo condition called sham surgery, which involves an invasive procedure (e.g., partial thickness...

  • Rapid Response Innovation Awards, 2007
    Re-distribution of Brain Gangliosides for Treatment of Parkinson's Disease

    Project Description:

    A pre-clinical model of Parkinson's disease can be generated by injecting MPTP, a toxin that results in specific damage to the same part of the brain that is damaged in Parkinson's...

  • Rapid Response Innovation Awards, 2007
    Neuroprotective effects of isradipine in a pre-clinical model of Parkinson’s disease

    Objective/Rationale: 
    Recent work by our group has shown that blocking L-type Ca2+ channels protects vulnerable dopaminergic neurons in three animal models Parkinson’s disease (PD). Isradipine, a high...

  • Rapid Response Innovation Awards, 2007
    Genetic characterization of Omi/Htra2 (PARK13) in autosomal dominant and sporadic Parkinson’s disease

    Objective/Rationale: 

    Identification of DNA variations that cause familial/sporadic parkinsonism has provided insight into the biological pathways involved in disease. Thirteen loci (PARK1-13) have...

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