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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Community Fast Track, 2004
    Neuregulin-2â: A Novel Trophic Factor for Midbrain Dopamine Neurons

    The continuing search for new and effective trophic factors as candidate therapeutics for treatment of Parkinson's disease is of great importance. This project will evaluate two proteins from the...

  • Community Fast Track, 2004
    DJ-1 Function in Dopaminergic Neuronal Function and Survival

    Parkinson's disease is the second most common neurodegenerative disease affecting the elderly. The movement disorder is caused by progressive loss of dopamine producing neurons. Loss of function...

  • Community Fast Track, 2004
    Gene Transfer of Pleiotrophin to Aged Parkinsonian Pre-Clinical Models

    Parkinson's disease involves the death of a specific population of neurons in the brain that supply the neurotransmitter dopamine (DA). A group of molecules termed neurotrophic factors have been...

  • Community Fast Track, 2004
    Maintenance of Nerve Terminals by Local Synthesis of Proteins in Axons

    Function of the nervous system depends on maintaining the connections between neurons throughout life. Loss of these synaptic connections is thought to be one of the early events in neurodegenerative...

  • Community Fast Track, 2004
    Dysregulation of Ubiquitylation in Parkinson's Disease

    It is now widely accepted that the ability to maintain appropriate levels of proteins is of fundamental importance to the normal function of neurons and other cells. The levels of many proteins are...

  • Community Fast Track, 2004
    Cytoprotective role of ABAD in Parkinson disease

    Mitochondrial dysfunction and loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) are the features of Parkinson's disease (PD). We have identified a multifunctional member of the...

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