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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2016
    Evaluation of LRRK2 Kinase Activity in Blood Cells

    Promising Outcomes of Original Grant:
    Since LRRK2 is a major genetic risk factor for Parkinson's disease (PD), much work has been devoted to LRRK2 function in neurons. However, LRRK2 is abundantly...

  • Research Grant, 2016
    MJFF Recruitment Centers of Excellence

    Study Rationale:
    Clinical trials and studies in Parkinson's disease (PD) are often limited by low enrollment of participants , increasing the time it takes to bring new therapies to the market. The...

  • Research Grant, 2016
    Inhibition of Striatal-enriched Phosphate (STEP) to Improve Parkinson-related Cognitive Dysfunction

    Promising Outcomes of Original Grant:
    Our original funded project was designed to examine absorption and distribution of the STEP (Striatal-Enriched Phosphatase), a protein associated with several...

  • Target Advancement Program, 2016
    Studying Monocyte Entry into the Brain in Alpha-synuclein-induced Parkinson's Disease

    Study Rationale:
    Alpha-synuclein is a sticky protein that clumps in the brains of people with Parkinson's disease (PD). In pre-clinical models, alpha-synuclein clumps attract scores of CCR2-positive...

  • Research Grant, 2016
    Patient-Carer-Provider Communication about the Impact of Motor and Non-motor Fluctuations

    Study Rationale:
    Temporary periods of poor mobility and other symptoms (OFF periods) are common in Parkinson’s disease and are associated with poorer quality of life. OFF symptoms are complex, with...

  • Improved Biomarkers and Clinical Outcome Measures, 2016
    Developing New Method for GBA sequencing and Detection of Germ-line or Somatic Point Mutations, Deletion/Insertions and Recombinations with the GBA Pseudo Gene

    Study Rationale:                   

    Mutations in the GBA gene are the most common genetic cause of Parkinson’s disease. This gene has a nearby pseudogene, which is a genetic material that is very...

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Our funding programs support basic, translational and clinical research from academia and industry.

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