The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Alpha-synuclein Pathology, 2014Development of Diagnostic Biomarker Tests for Parkinson’s Disease
Study Rationale:
An early diagnostic test to identify those with Parkinson’s disease (PD) and to intervene with therapies as early as possible is a critical unmet need. Recent studies have... -
Research Grant, 2014Development and Validation of Biomarker Assays for Improved Diagnosis of Parkinson’s Disease: The Second Generation of Synuclein Assays
Study Rationale:
Lewy bodies composed primarily of the protein alpha-synuclein are important hallmarks of Parkinson’s disease (PD). Available data on the clinical use of alpha... -
Research Grant, 2014Genetic Predictors of Prognosis: GBA and SNCA Meta-Analysis Project
Study Rationale:
Predicting the prognosis of Parkinson’s disease (PD) for a patient is currently not possible. Genetic predictors of prognosis would help inform clinical trial design... -
Access to Data and Biospecimens, 2014Analysis of Brain and Peripheral Small Molecule Levels in Parkinson’s Disease
Study Rationale:
Parkinson’s disease is accompanied by a loss of chemical signaling molecules in the brain and body. For instance, chemicals like dopamine are lost in both the gut and in the brain... -
Rapid Response Innovation Awards, 2014Exploration of Relationships and Formulations of Molecular Tweezers
Study Rationale:
A key mechanism leading to death of neurons in the brain is formation of toxic clumps of the protein alpha-synuclein. Therefore blocking the formation of these toxic... -
Access to Data and Biospecimens, 2014Verification of a Long, Non-coding RNA in Blood as a Biomarker for Parkinson's Disease
Study Rationale:
We have discovered a long, non-coding RNA (RNA that does not encode a protein) that shows a five-fold decrease within the brains of people with Parkinson’s disease (PD) compared...
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Our funding programs support basic, translational and clinical research from academia and industry.