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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Novel Approaches to Drug Discovery for Parkinson's Disease, 2009
    Cerium Oxide Nanoparticles in Treatment of Parkinson's Disease

    Objective/Rationale:
    Nanotechnology and nanomedicine hold potential to advance medical treatment through construction of materials with enhanced biological effects, at the atomic scale. By...

  • Novel Approaches to Drug Discovery for Parkinson's Disease, 2009
    Novel JNK Inhibitors as Therapeutic Agents for Parkinson's Disease

    Objective/Rationale:
    Our objective is to test the in vivo pharmacokinetic profile, mode of action and efficacy of two novel and highly selective JNK inhibitors in the MPTP (1-methyl-4-phenyl-1,2,3,6...

  • Program-non-specific Funding, 2009
    LRRK2 Variation in Parkinson's Disease

    Objective/Rationale:
    Over the last decade genetic causes of Parkinson’s disease have given great insights into the pathways and mechanisms that play a role in the disease. The discovery of common...

  • Program-non-specific Funding, 2009
    Delivery of Kinase-Modified LRRK2 to Dopaminergic Neurons Using High-Capacity Viral Vectors

    Promising Outcomes of Original Grant:
    Mutations in LRRK2 are the most common known cause of PD, and LRRK2 demonstrates kinase-dependent neurotoxicity in vitro but these results have not been confirmed...

  • Program-non-specific Funding, 2009
    Immunology and bio activity of regulated rAAV1-GDNF in pre-clinical models of PD

    Objective/Rationale:
    Clinical trials with a trophic factor called GDNF, where GDNF is injected directly in the brain by pumps, have not been completely successful. Many scientists believe that the...

  • Program-non-specific Funding, 2009
    Time Course of TNF-alpha Expression and Oxidative Stress after Intrastriatal 6-OHDA

    Objective/Rationale:
    Animal models of Parkinson’s disease can provide investigators with tools to examine the causes of the disease itself as well as potential therapies for treatment. One of the most...

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Our funding programs support basic, translational and clinical research from academia and industry.

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