The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Therapeutics Development Initiative, 2008Spectroscopy of Human Plasma for Diagnosis of Idiopathic Parkinson's Disease
Objective/Rationale:
The diagnosis of Parkinson disease is based on clinical criteria and is labor-intensive, expensive and often inconclusive. Unfortunately, there are currently no accepted...
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Therapeutics Development Initiative, 2008Hif Prolyl Hydroxylase Inhibitors: New Treatment Potential against Parkinson's Disease
Hif prolyl hydroxylase (HPH) has been identified as one of the genes regulated in the brains of Parkinson’s disease patients. Recent research data suggest that HPH is involved in the mechanism...
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Rapid Response Innovation Awards, 2008Viral over-expression of alpha synuclein in young and aged pre-clinical models: Can we model young onset versus aged onset PD?
Objective/Rationale:
Patients with young onset Parkinson’s disease and patients with aged onset Parkinson’s disease differ in their course with young onset patients displaying a less malignant course... -
Rapid Response Innovation Awards, 2008Neuropathological Analyses of Long-term Fetal Nigral Transplants in Patients with Parkinson's Disease
Objective/Rationale:
In an attempt to replace dopamine expressing neurons that die in Parkinson’s disease patients have received grafts of fetal dopamine-containing cells. Over time, these patients... -
Rapid Response Innovation Awards, 2008Can the electrocardiogram be used to identify pre-motor Parkinson's Disease
Objective/Rationale:
Loss of cardiac autonomic innervation is a near universal feature in Parkinson’s disease. In this proposal, we will determine if this feature of PD occurs before motor symptoms... -
Rapid Response Innovation Awards, 2008A Randomized, Double-Blind, Trial of Nexalin® vs. Placebo in Subjects with Early Parkinson's Disease
Objective/Rationale:
While the oral medications to treat PD are often quite effective in treating the physical symptoms (motor symptoms) such as tremor and stiffness, they may be associated with side...
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Our funding programs support basic, translational and clinical research from academia and industry.