The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Critical Challenges in PD: Postural Instability and Gait Dis, 2012Targeted Cognitive Training Program for Freezing of Gait
Promising Outcomes of Original Grant:
In our original study we investigated the processes underlying the freezing phenomenon in PD. In this work we found symptoms of freezing of gait (FOG) could be... -
Rapid Response Innovation Awards, 2012Is the Xenomitochondrial Pre-clinical model an ‘Ideal’ Parkinson’s Disease Model?
Objective/Rationale:
The lack of a pre-clinical model that exhibits key features of human Parkinson’s disease is an impediment to research progress. In this project we will determine whether a novel... -
MJFF Research Grant, 2012The Role of Alpha-synuclein in the Pathogenesis of Parkinson’s Disease in a Pre-clinical Model
Objective/Rationale:
Preliminary data from our laboratory demonstrated that the protein alpha synuclein (a-syn) might play a major role in an inherited autosomal recessive pre-clinical model for... -
Rapid Response Innovation Awards, 2012Polyglutamine Repeats and Parkinson Disease
Objective/Rationale:
Trinucleotide repeat expansion is a gene mutation where the codons (the groups of DNA components that correspond to amino acids) exceed the maximum of a certain gene... -
Target Validation, 2011The Sigma 1 Receptor as a Target for Disease-modifying Therapies in Parkinson's Disease
Objective/Rationale:
The Sigma-1 receptor (Sig-1R) is a protein involved in the transport of lipids and proteins between organelles within the cell. Impairment of these intracellular trafficking... -
Target Validation, 2011Validation of Dorsal Column Electrical Stimulation as a Target for Parkinson's Disease Therapy
Objective/Rationale:
Direct electrical stimulation of certain areas of the brain is an effective method to treat the motor symptoms of Parkinson’s, but it requires the insertion of electrodes into the...
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Our funding programs support basic, translational and clinical research from academia and industry.