The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2018A ROCK Inhibitor as a Neuroprotective Therapy for Parkinson's Disease
Study Rationale:
In the past, we demonstrated that using drugs to deactivate Rho-associated protein kinase (ROCK), a protein regulating shape and movement of cells, can protect dopamine-producing... -
Research Grant, 2018Tracking Mobility and Symptoms of Parkinson's Disease with New Wireless Technology
Study Rationale:
As wearable technology -- smartphones and wearable devices with built-in sensors -- became increasingly more common, affordable and effective, its use in the evaluation and treatment... -
Inflammation Biomarkers Program, 2018Using Changes in Immune Cells to Diagnose or Track Parkinson's Disease
Study Rationale:
There are currently no Parkinson's disease (PD) biomarkers -- objective measures of disease -- in clinical use, but several blood biomarkers are being developed. Some of these... -
Research Grant, 2018A Global Search for People with a Rare, Inherited Form of Parkinson's Disease
Study Rationale:
Mutations, or changes, in the genes PRKN and PINK1 cause inherited Parkinson's disease (PD) that starts at an early age. This type of Parkinson's accounts for roughly 13 percent of... -
Target Advancement Program, 2018Causes, Mechanism and Consequences of an Energy Crisis in Striatal Nerve Endings
Study Rationale:
Two proteins, PINK1 and parkin, prevent cell death by breaking down damaged mitochondria, cell's energy generators. Mutations in the PINK1/PRKN genes - genetic changes that render... -
Target Advancement Program, 2018Neuroprotective Effects of NFE2L1 in Parkinson's Models
Study Rationale:
NFE2L1 is a protein that controls the expression of genes involved in the differentiation and survival of dopamine neurons. NFE2L1 levels are reduced in dopamine neurons in the brains...
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Our funding programs support basic, translational and clinical research from academia and industry.