The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
-
Research Grant, 2018Functional Fine-mapping of LRRK2 Locus
Study Rationale:
Genetic studies for Parkinson's disease have indicated that variants of the LRRK2 gene are associated with increased risk of Parkinson's disease. However, we still know very little... -
Research Grant, 2018Optimization of Probe-ELISA Parkin Activity Assay
Promising Outcomes of Original Grant:
Certain forms of Parkinson's are due to defects in a cellular regulatory node known as the PINK1-Parkin pathway. With previous funding from MJFF, we sought to... -
Research Grant, 2018Evaluating the Therapeutic Potential of the Systemic Antagonism of Dopamine Receptor D3
Promising Outcomes of Original Grant:
Parkinson's disease involves toxic forms of certain proteins (e.g., alpha-synuclein) in the brain, which trigger an immune response driven by inflammatory... -
Research Grant, 2018Structure-Based Design of Small-Molecule Activators of Parkin
Promising Outcomes of Original Grant:
The protein Parkin requires activation by another enzyme called PINK1. With previous MJFF funding, we identified a new class of chemical fragments that could be... -
Target Advancement Program, 2018Validating Astrocyte-produced Protein GDF15 as a Novel Neuroprotective Therapy
Study Rationale:
In Parkinson's disease (PD), death of dopamine-producing brain cells takes place mainly the substantia nigra pars compacta (SN) but not in the neighboring ventral tegmental area (VTA)... -
Target Advancement Program, 2018Testing the Ability of Clenbuterol to Prevent or Modify the Course of Parkinson's Disease
Study Rationale:
Protein alpha-synuclein clumps in the brains of people with Parkinson's disease (PD), forming Lewy bodies. Recent studies have suggested that beta-2 adrenoreceptor agonists -- drugs...
Apply for a Grant
Our funding programs support basic, translational and clinical research from academia and industry.