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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Therapeutic Pipeline Program, 2018
    The PERSPECTIVE study: Personalized Speech Therapy for Active Conversation

    Study Rationale:
    Many people with Parkinson's disease have speech problems, which can be overcome by instructing patients to intentionally speak louder. However, to use this technique in daily life...

  • Inflammation Biomarkers Program, 2018
    Studying Age-related Chronic Inflammation in Parkinson's Disease

    Study Rationale:
    Aging increases the risk of Parkinson's disease (PD), making the disease more likely to occur at an older age. It is unclear how biological changes that accompany normal aging are...

  • Inflammation Biomarkers Program, 2018
    Studying Abnormalities of Immune System Aging in Parkinson's Disease

    Study Rationale:
    While immune cells protect us from infection, they can also cause damage by inadvertently responding to other, non-infectious events. Such immune response occurs in Parkinson's disease...

  • Research Grant, 2018
    Studying Structures of LRRK2 to Understand and Slow Parkinson's Disease

    Study Rationale:
    Mutations in the LRRK2 gene are a leading genetic cause of Parkinson's disease (PD) and cause dysfunction in the LRRK2 protein. We are studying the structures of normal and abnormal...

  • Inflammation Biomarkers Program, 2018
    Influence of Inflammation on Symptoms and Progression of Parkinson's Disease

    Study Rationale:
    Symptoms of Parkinson's disease (PD) are different for different people, suggesting a strong influence of genetic and/or non-genetic factors, including inflammation. While many...

  • Improved Biomarkers and Clinical Outcome Measures, 2018
    The Role of Circular RNAs in Parkinson's Disease and Dementia

    Study Rationale:
    Biomarkers are objectively measurable characteristics that can be used to diagnose a disease or to track its progression. In this study, we will explore circular RNAs -- a recently...

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