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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2023
    Evaluating a Gene Therapy that Restores Mitochondrial Function as a Treatment for Parkinson’s Disease

    Study Rationale: Currently, all treatments for Parkinson’s disease (PD) aim to improve symptoms by restoring or maintaining the levels of dopamine in the brain. No treatment on the market slows or...

  • Research Grant, 2023
    Validation of Gap Junction Proteins as a New Therapeutic Target for Impeding the Cell-to-cell Spread of Alpha-synuclein in Parkinson’s Disease and Related Synucleinopathies

    Study Rationale:The gap junctions that directly connect one cell with its neighbor have recently been implicated in the transfer of alpha-synuclein pathology associated with Parkinson’s disease (PD)...

  • Spring 2022 RFP: Proof-of-Concept Testing of PD Therapeutics, 2022
    Preclinical Models and Therapies for the Gastrointestinal Symptoms of Parkinson’s Disease

    Study Rationale: In addition to the well-recognized movement abnormalities associated with Parkinson’s disease (PD), gastrointestinal symptoms such as constipation, leaky gut and inflammation are also...

  • Research Grant, 2022
    Evaluation of Assessments Made by Digital Health Technology

    Study Rationale: The development of drugs that can slow or halt the progression of Parkinson’s disease (PD) can be expensive and take a long time. Although there are many promising new therapeutics in...

  • Research Grant, 2022
    Extending Assessment of WATCH-PD Remote Digital Technology

    Study Rationale: Digital tools can provide objective, sensitive, real-world measures of Parkinson’s disease (PD). Better measures could lead to more efficient, patient-centric and timely evaluation of...

  • Research Resources Imaging Program, 2022
    Developing Actionable Machine Learning (AML) Methods for Diagnosing, Monitoring and Treating Parkinson’s Disease

    Study Rationale: In today’s modern age of computational smart health, actionable machine learning (AML) methods automatically and progressively learn how to correctly answer queries about the state of...

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