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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Fall 2021 RFP: Outcome Measures, 2022
    Development of Standardized Measurements for Monitoring the Progression of Parkinson’s Disease via MRI

    Study Rationale: One of the difficulties in research towards new treatments in Parkinson’s disease (PD) is the diversity of disease presentations and the lack of tools to measure the effect of a...

  • , 2022
    Studying the Epidemiology of Parkinson’s Disease in Latin America: Learning from Underrepresented Populations

    Study Rationale: Initial evidence has shown that the global distribution of Parkinson’s disease (PD) may vary; however, little is known about the prevalence of PD across large parts of the world. This...

  • Diversity, Equity and Inclusivity in Parkinson's research, 2022
    Risk Factors for Parkinson’s Disease Among Participants in the Black Women’s Health Study

    Study Rationale: Little is known about the incidence, clinical presentation and risk factors for Parkinson’s disease (PD) in Black women, yet the existing evidence suggest that they may have a worse...

  • Fall 2021 RFP: Accelerating Early Proof-of-Concept Testing of Promising PD Therapies, 2022
    Using “Nanobodies” to Prevent Formation of Intracellular Alpha-synuclein Aggregates

    Study Rationale: The aggregation of a structurally abnormal form of the protein alpha-synuclein appears to be responsible for the initiation and progression of Parkinson’s disease (PD). In previous...

  • Alpha-synuclein Seed Amplification Assay Program, 2022
    Development of a Reliable Diagnostic Test for Parkinson’s Disease Using Patient Blood Samples

    Study Rationale: Although diagnosis of Parkinson’s disease (PD) is crucial for the success of treatment, especially in the early stages, there are still no biomarkers available for use as a reliable...

  • Fall 2021 RFP: Accelerating Early Proof-of-Concept Testing of Promising PD Therapies, 2022
    Inhibiting Lrrk2 Specifically in the Brain

    Study Rationale: Neurodegenerative disorders such as Parkinson’s disease (PD) affect the brain. Some of the drugs designed to treat PD have unwanted side effects in the rest of the body. To minimize...

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