The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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The Role of Inflammation in Parkinson's Disease, 2003Activation of Receptor for Advanced Glycation Endproducts (RAGE) on Microglia: A Novel Inflammatory Mechanism Contributing to PD Pathogenesis
There is now considerable and growing evidence that Parkinson's disease (PD) is associated with inflammation in the brain. Several small soluble proteins that are commonly secreted during inflammatory...
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The Role of Inflammation in Parkinson's Disease, 2003The role of IAP-induction in mediation of rythropoietin-induced neuroprotection in rodent models of Parkinson’s disease
Systemic administration of erythropoietin (EPO) has been shown to reduce neuronal cell death and neurological dysfunction in animal models of stroke, epilepsy, head injury and multiple sclerosis (MS)...
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The Role of Inflammation in Parkinson's Disease, 2003The Role of Subclinical Rejection in Graft-mediated Dyskinesias
The results of two recent Parkinson's disease (PD) clinical trials designed to replace cells lost to the disease have documented that replacing these cells can have negative side effects. In...
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The Role of Inflammation in Parkinson's Disease, 2003Studies on the effects of peripheral inflammation on the progression of Parkinson ´s disease
Inflammation is the first line of defense of the organism after an insult is detected. Although usually beneficial, it could be detrimental if its magnitude or duration is not adequate. In the brain...
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The Role of Inflammation in Parkinson's Disease, 2003Involvement of CD200/CD200 Receptor Interactions in Inflammatory-mediated Pathology in PD
Inflammation has been shown in many diseases to be a destructive process when occurring under inappropriate circumstances. Based on a wide range of studies, it appears that dopaminergic neurons in the...
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The Role of Inflammation in Parkinson's Disease, 2003Activation of neuroinflammatory glial response by neuromelanin, its role in neurodegeneration, and therapeutic strategies for Parkinson's disease
In Parkinson's disease a preferential loss of neurons containing neuromelanin occurs with respect to the neurons which do not contain neuromelanin. We have previously shown that neuromelanin inside...
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