The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Biomarkers Across Neurodegenerative Diseases, 2016Cross-disease Brain Image Modeling
Study Rationale:
Individuals with Alzheimer’s and Parkinson’s diseases share typical brain image patterns. The research field has long awaited an intelligent system that could interpret patterns...
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Target Advancement Program, 2016Validation of Cyclin-G Associated kinase (GAK) as a Target for Parkinson's Disease
Study Rationale:
The project will investigate Cyclin-G associated kinase (GAK), a candidate risk gene for Parkinson’s disease (PD), based on genome-wide association studies (GWAS)...
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Target Advancement Program, 2016Insights into LRRK2 Kinase Inhibitors
Study Rationale:
Mutations in LRRK2 cause an inherited form of Parkinson's disease (PD), and variations in LRRK2 can increase disease risk, indicating that the protein is key in the entire PD disease... -
Therapeutic Pipeline Program, 2016Novel LRRK2 Antisense Oligonucleotides as a Therapy for Parkinson's Disease
Study Rationale:
LRRK2 gain-of-function gene mutations (R1441C and G2019S) are one of the most prevalent mutations contributing to inherited Parkinson's disease (PD). Altered LRRK2 function has also... -
Target Advancement Program, 2016The Role of LRRK2 in Neuronal Calcium Maintenance
Study Rationale:
Calcium is essential for neuronal survival and function. Flawed intracellular calcium homeostasis (maintenance) is linked to neurodegeneration. There is, however, a major knowledge... -
Research Grant, 2016Tau Imaging in Parkinson's Disease
Study Rationale:
A substantial proportion of individuals with Parkinson's disease develop cognitive
impairment, or difficulty with thinking abilities. The basis for these changes is poorly
understood. We...
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Our funding programs support basic, translational and clinical research from academia and industry.