The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Improved Biomarkers and Clinical Outcome Measures, 2015Measuring Altered White Blood Cell Functionality as a Biomarker of Parkinson’s Disease
Study Rationale:
White blood cells from people with Parkinson’s disease (PD) patients appear to differ from those of control individuals in that there are differences in the set of genes that are... -
Research Grant Supplement, 2015The Influence of Bacterial Amyloid on Alpha-synuclein Misfolding in a Pre-clinical Model Supplement
Promising Outcomes of Original Grant:
We hypothesized that that deposits of the Parkinson’s disease-associated protein alpha-synuclein in gut and brain neurons are caused by exposure to proteins of... -
Research Grant Supplement, 2015Modulation of MicroRNA Activities in Parkinson's Disease
Objective/Rationale:
Previous data support that small non-coding gene regulatory RNAs, known as microRNAs, are dysregulated in Parkinson’s disease (PD). However, the disease-relevance of these changes... -
Improved Biomarkers and Clinical Outcome Measures, 2015Method to Quantify Parkinsonian Motor Signs for Interventional Drug Trials
Study Rationale:
Current methods to evaluate motor impairments in Parkinson’s disease rely on subjective examinations. Our team seeks to develop an objective assessment of motor... -
Research Grant, 2015Parallel Reaction Monitoring within the Parkin Ubiquitin Ligase System
Study Rationale:
Recent studies have revealed a role for PINK1 and PARKIN, two genes mutated in early onset Parkinson’s disease, function to promote a cellular process called ubiquitylation of... -
Therapeutic Pipeline Program, 2015Effects of Transcranial Stimulation on Freezing of Gait in Parkinson's Disease
Study Rationale:
Many people with Parkinson's disease experience freezing of gait, when the person is unable to move forward, despite his or her best efforts. Although it is not exactly clear why or...
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Our funding programs support basic, translational and clinical research from academia and industry.