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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Rapid Response Innovation Awards, 2014
    Optogenetics-based, Photo-switchable Model of Parkinson’s Disease for Drug Screening

    Objective/Rationale:
    Neurodegeneration has proven notoriously difficult to study. The main barrier to progress has been the challenging, heterogeneous nature of brain tissue. Optogenetics is a...

  • Research Grant Supplement, 2014
    GluN2D Antagonism in the Subthalamic Nucleus for the Treatment of Parkinsonism

    Promising Outcomes of Original Grant:
    The goal of the original grant was to identify new chemical compounds that block specific types of receptors for the neurotransmitter glutamate and test whether...

  • Rapid Response Innovation Awards, 2014
    Motor Proteins as Novel Drug Targets of Disease-modifying Treatments for Parkinson’s Disease

    Objective/Rationale:
    More and more research suggests that part of the cellular quality control mechanism, which degrades abnormal proteins or damaged parts of the cell, is defective in Parkinson’s...

  • Research Grant, 2014
    Probing Nurr1 Expression in Parkinson’s Disease

    Objective/Rationale:
    Impaired function of the hormone receptor Nurr1 might contribute to the pathogenesis of Parkinson’s disease (PD) and is an active target for novel therapeutics. Previous studies...

  • Access to Data and Biospecimens, 2014
    Diffusion Tensor-based Biomarker for Parkinson's Disease

    Objective/Rationale:             
    Magnetic resonance imaging (MRI) is a common tool used to diagnose or evaluate brain diseases such as Parkinson’s disease. Typically, MRI images are read by a...

  • Rapid Response Innovation Awards, 2014
    Inhibition of Striatal-Enriched Phosphatase (STEP) to Improve Parkinson-Related Cognitive Dysfunction

    Study Rationale:                   
    As the enzyme striatal-enriched phosphatase (STEP) may be abnormally elevated in aged parkinsonian pre-clinical models with cognitive deficits, the possibility...

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Our funding programs support basic, translational and clinical research from academia and industry.

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