The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2014Efficacy and Safety of APL-130277 in People with Parkinson’s Disease who are Apomorphine Naïve
Study Rationale:
Apomorphine is a drug that is used to control “off” episodes in people with Parkinson’s disease. At present, the drug is given by injection under the skin and starts... -
Therapeutic Pipeline Program, 2014Effects on Gait and Balance of Augmenting Cholinergic Function
Study Rationale:
Impairments of gait and balance are common and life-altering in patients with Parkinson’s disease (PD). These impairments are incompletely controlled with... -
Research Grant, 2014Parkinson's Disease Biomarker Discovery and Verification Using Multiple Reaction Monitoring
Study Rationale:
Multiple candidate Parkinson’s disease (PD) biomarkers have been identified over the years, but none have been properly validated. Using a targeted mass spectrometry platform, a... -
Target Validation, 2014Targeting Internalization and Aggregation of Alpha-synuclein Proteopathic Seeds with Glycosaminoglycan Interacting Small Molecules (GISMO)
Objective/Rationale:
Evidence points to key roles for alpha-synuclein and cell-surface glycosaminoglycans (GAGs) — a type of carbohydrate molecules — in the onset of neurodegenerative... -
Research Grant, 2014Novel Nicotinic Receptor Agonist for Treating Levodopa-induced Dyskinesia
Promising Outcomes of Original Grant:
Our initial hypothesis was two-fold: first, that specific nicotinic (chemical messenger) receptor subtypes are involved in nervous system responses to levodopa and... -
MJFF Research Grant, 2013Predicting Parkinson’s Disease with Smartphone Data
Objective/Rationale:
The purpose of The Michael J. Fox Foundation’s Parkinson’s Data Challenge was to develop a way to help patients and clinicians using objective, passively collected...
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Our funding programs support basic, translational and clinical research from academia and industry.