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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • MJFF Research Grant, 2011
    Ghrelin Concentrations in CSF and Corresponding Serum Samples in PD Patients and Controls

    Objective/Rationale:
    The aim of this study is to establish a valid method for measuring ghrelin concentrations in human cerebrospinal fluid samples. Ghrelin is an appetite-stimulating hormone with...

  • Rapid Response Innovation Awards, 2011
    Psychological Stress as a Risk Factor for Parkinson's Disease

    Objective/Rationale: 
    All persons experience psychological stress. In fact, its pervasiveness is the primary cause of countless diseases. Although the impact of psychological stress on Parkinson’s...

  • Rapid Response Innovation Awards, 2011
    Assessment of AAV Transduction with Wildtype and Constitutively Active p70S6K to Induce Axon Re-Growth in Dopamine Neurons

    Objective/Rationale:
    Available treatments for PD offer relief of symptoms, but none are able to restore the neural structures that have degenerated. Neuroscientists have long believed that surviving...

  • Rapid Response Innovation Awards, 2011
    Xenon Neuroprotection in a Pre-clinical Parkinson's Model

    Objective/Rationale: 
    Xenon is an anesthetic gas known to have an excellent safety profile. Recent research suggests that xenon administered at subanesthetic concentrations is neuroprotective in acute...

  • Rapid Response Innovation Awards, 2011
    Fractalkine-CX3Cr1 Signaling in Models of Parkinson Disease: Quest for Novel Therapeutic Strategies

    Objective/Rationale: 
    Microglia, one of the key players in neuroinflammation, are increased in number and activated in the brains of Parkinson’s disease (PD) or pre-clinical models of PD. A recent...

  • Rapid Response Innovation Awards, 2011
    The Development of Novel Adeno-associated Virus Vectors for Intravenous Parkinson's Gene Therapy

    Objective/Rationale:
    As Parkinson disease progresses, a wide range of brain areas exhibit evidence of inflammation and degeneration, but presently no therapies exist that selectively target these...

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