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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Understanding LRRK2 Biology, 2009
    Development of Biochemical Assays for LRRK1

    Objective/Rationale
    Studies over the last several years have identified the protein kinase LRRK2 as a potential target for Parkinson’s disease therapeutics.  While targeting kinases has been a...

  • Biomarkers, 2009
    T-Cell Receptors Changes as a Biomarker of Parkinson's Disease

    Objective/Rationale:
    The diagnosis of PD is based on clinical characteristics because there are no reliable blood tests for early diagnosis or to follow the progressive course of the disease. Along...

  • Rapid Response Innovation Awards, 2009
    Defining Genetic Factors for PD in a Conserved Population

    Objective/Rationale
    The identification of genes underlying risk for Parkinson’s disease (PD) helps to further the understanding of this complex disorder, with the discovery of new genes contributing...

  • Program-non-specific Funding, 2009
    Data Repository for Experimental Data

    Objective/Rationale
    Synthesizing biomedical data into effective discoveries is greatly hampered by the way science is both reported in research articles and stored in databases. Articles do not...

  • Rapid Response Innovation Awards, 2009
    Development of Potent Conformation-Specific Compounds Directed to Monomeric Alpha-Synuclein

    Promising Outcomes of Original Grant:
    The goal of our original funded grant was to use our alpha-synuclein assay to identify compounds that prevent conformational change to the fully open form of the...

  • Rapid Response Innovation Awards, 2009
    Evaluation of a Viral Non-coding RNA as a Neuroprotective and Neurorestorative Therapy in Chronic Models of Parkinson's Disease

    Promising Outcomes of Original Grant:
    Previously, we asked whether a novel viral non-coding RNA (an RNA which does not appear to encode a protein), but with known pro-life functions, could act to...

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