The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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MJFF Research Grant, 2008The anatomic basis of cardiac and cognitive changes in Parkinson's disease: A collaborative study with the Parkinson's Institute, Sunnyvale, CA (USA)
Objective/Rationale:
The heart, particularly the conduction system, is influenced by the parasympathetic and sympathetic nervous systems. Recently, early-occurring Parkinson’s disease-related Lewy... -
Program-non-specific Funding, 2008Evaluation of Pioglitazone CSF Penetration
Promising Outcomes of Original Grant:
In our original grant we assessed whether the antidiabetic compound pioglitazone can be neuroprotective in a non-human primate model of Parkinson’s disease. We... -
Program-non-specific Funding, 2008Evaluation of Neuroprotective Properties of Selective PPAR Gamma Agonist LY554862
Objective/Rationale:
Low-risk, easily administered therapies aiming to slow down or stop neurodegeneration in PD are urgently needed. Compounds that activate PPAR gamma receptors have the potential to... -
MJFF Research Grant, 2008Evaluation of Gastrointestinal Motility in Parkinsonian Rodents
Objective/Rationale:
Gastrointestinal (GI) symptoms, such as nausea, bloating, and constipation occur in nearly every patient afflicted with Parkinson’s Disease (PD) at some point in their illness... -
MJFF Research Grant, 2008Are Anti-Parkinsonian Treatments Disease Modifying?
Objective/Rationale:
Current treatments of Parkinson’s disease are not thought to slow the progression of the disease but just appear to result in temporary relief of symptoms. There is some evidence... -
MJFF Research Grant, 2008QE3 Trial Ancillary Biomarkers Study
Objective/Rationale:
The QE3 trial is a large multicenter clinical trial designed to determine whether the nutritional supplement coenzyme Q10, which traps a potentially dangerous type of chemical in...
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Our funding programs support basic, translational and clinical research from academia and industry.