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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Postural Instability and Gait Disturbances, 2009
    Neuroanatomical Correlates of Dopamine Responsive and Non-responsive Gait and Balance Impairment in Parkinson's Disease

    Objective/Rationale:
    Parkinson’s is more than a motor disorder that responds to dopamine replacement. Dopamine non-responsive features account for much of the disability that develops with disease...

  • Postural Instability and Gait Disturbances, 2009
    Relationship between REM Behavior Disorder and Freezing of Gait in Parkinson's Disease

    Objective/Rationale:
    Many people with REM sleep behavior disorder (RBD), a disease associated with disturbance of sleep, eventually develop Parkinson’s disease. Dysfunction and degeneration of...

  • Postural Instability and Gait Disturbances, 2009
    Determining the Neural Correlates of Freezing of Gait in Parkinson's Disease Using Functional Magnetic Resonance Imaging

    Objective/Rationale:
    Freezing of Gait (FOG) in Parkinson’s disease occurs when a person’s feet become suddenly ‘frozen’ while walking or turning. FOG is a leading cause of falls, and responds poorly to...

  • Postural Instability and Gait Disturbances, 2009
    The Role of White Matter Pathology in the Development of the Postural Instability and Gait Disturbance (PIGD) Type of Parkinson's Disease (PD)-1

    Objective/Rationale:
    It is not clear why a subset of patients with Parkinson's disease develop postural instability and gait disturbances (PIGD), while others do not. White matter (WM) changes that...

  • MJFF Research Grant, 2009
    Pilot Assessment of the Effect of Optimism and Expectation on Dyskinesia Rating Scales in Parkinson's Disease Subjects Randomized to Placebo or Amantadine

    Objective/Rationale:
    The effects of placebo response in clinical and surgical interventions in PD have become increasingly recognized. Many factors have been associated with placebo response including...

  • Therapeutics Development Initiative, 2009
    IMD-026259 An Innovative Drug for Disease-Modifying Treatment of Parkinson´s Disease

    Objective/Rationale:
    Parkinson’s disease progresses through the death of brain cells caused by “oxidative stress.” This takes place in dysfunctional mitochondria - structures within each cell...

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