The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Molecular Mechanisms of Dyskinesia in Parkinson's Disease, 2003Anatomical and neurochemical characterization of basal ganglia neuropeptides in levodopainduceddyskinesia
The most common treatment for Parkinson's disease is levodopa (L-DOPA). This usually gives good relief of symptom for many years but, eventually, complications such as abnormal involuntary movements...
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Molecular Mechanisms of Dyskinesia in Parkinson's Disease, 2003Reversal of Dyskinesias By in-vivo Gene Transfer of L-DOPA Using Adeno-associated Viral Vectors
Parkinson's disease is a result of an extensive loss of the pigmented neurons located in the brain stem (termed the Substantia Nigra). These nerve cells are the principal neurons producing dopamine in...
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Community Fast Track, 2003Methionine Sulfoxide Reductase A CMRSA and Parkinson’s Disease Pathogenesis
There is a large body of evidence that both defective energy metabolism as well as oxidative damage, which is a consequence of increased production of free radicals, may play a critical role in...
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Community Fast Track, 2003Multi-single Unit Electrophysiological Characterization of Dyskinesia Induced by Dopamimetic Drugs
Parkinsonian patients develop debilitating motor complications caused by the best treatments of the disease, the levodopa and the dopamine agonists. Among other phenomena, it is known that these...
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Community Fast Track, 2003Reconstructing the neural circuits in Parkinson’s, using biodegradablepolymer bridges or striatal co-grafts to encourage neural outgrowth from transplantedtissue
In Parkinson's disease, the neurocircuitry, called the nigrostriatal pathway, is lost. This pathway links the substantia nigra to the striatum. In neural tissue transplants for Parkinson's disease...
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Community Fast Track, 2003Effects of Subthalamic Nucleus Stimulation on Sensorimotor Integration
In addition to the well-known motor symptoms, sensory symptoms are also common and sensory abnormalities have been documented in Parkinson's disease (PD). Although deep brain stimulation (DBS) of the...
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Our funding programs support basic, translational and clinical research from academia and industry.