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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Community Fast Track, 2003
    Biomarker Discovery in Parkinson’s Disease

    The primary goal of our studies is to expand our ongoing biomarker discovery program in order to establish biological markers of Parkinson's disease (PD). The imperative to develop effective therapies...

  • Community Fast Track, 2003
    Mitochondrial Trafficking in Dopaminergic Neuron Injury

    Mitochondria are considered to be the "power house" of all cells, including neurons, because they convert food into energy in the form that cells can use. When mitochondria fail, cells typically die...

  • LEAPS, 2003
    High Resolution Whole Genome Study to Determine Genetic Loci of Parkinson's Disease

    The Cox team will leverage Perlegen's high-density array technology and the Mayo Clinic's extensive patient database, clinical expertise and DNA bank to create a genetic map of causes and risk factors...

  • The Role of Inflammation in Parkinson's Disease, 2003
    Spiral Inflammation Hypothesis of Parkinson’ Disease

    It is well known that autopsied brains from patients with Parkinson's disease (PD) show evidence of inflammation within the region of the brain thought to be responsible for PD â€" the substantia...

  • The Role of Inflammation in Parkinson's Disease, 2003
    Role of lymphocyte brain infiltration in neuroinflammation and nerve cell death in Parkinson’s disease

    Parkinson's disease is characterized by a slow progression of a specific neuronal population in the brain using dopamine as neurotransmitter. Previous studies performed by several groups of...

  • The Role of Inflammation in Parkinson's Disease, 2003
    Significance of Complement Activation in the Progression of Parkinson's disease

    The complement system is composed of a series of proteins which react with each other in an orderly fashion, producing protein fragments (so-called 'complement activation proteins') which can exert...

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