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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Biomarkers, 2002
    State & Trait Markers for Parkinson's Disease in CSF, Plasma, & Urine from Datatop

    Although the clinical features of Parkinson's disease (PD) and its changes in the brain are unmistakable, it lacks identified biochemical clues that could enhance early diagnosis of this disorder. We...

  • Biomarkers, 2002
    Characterization of Alpha Synuclein in Human Fluids & Brain as a Biomarker for Parkinson's Disease

    To date there is no readily accessible laboratory test available for the diagnosis of Parkinson disease. The diagnosis of probable PD is generally made over time by a neurologist who serially examines...

  • Fast Track, 2002
    Parkinson's and the Regulation of Neuronal Survival

    Parkinson's disease (PD) is an important neurological disorder that afflicts over one million North Americans and is characterized by gait difficulty, rigidity, and tremor. Although Symptoms & Side...

  • Fast Track, 2002
    Prospective study of nonsteroidal antiinflammatory drugs and risk of PD

    Although the exact cause of Parkinson's disease is unknown, the results of animal experiments and postmortem studies among individuals with Parkinson's disease suggest that inflammation may contribute...

  • Fast Track, 2002
    Levodopa-induced dyskinesias result from dysregulation of intraneuronal trafficking of dopamine receptors

    Involuntary movements, or dyskinesias, represent a debilitating complication of levodopa therapy for Parkinson's disease experienced by the vast majority of the patients. We hypothesize that...

  • Fast Track, 2002
    Alterations of the distribution and of the subunit composition of the N-methyl-D-aspartate receptors in the basal ganglia of the parkinsonian rat

    The loss of the dopamine-containing neurons of the substantia nigra, the major hallmark of Parkinson's disease, leads to many 'knock-on' effects in the brain, which include both structural and...

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