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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Community Fast Track, 2002
    VDA Agonist Neuroprotection via AKT Pathway in MPTP Pre-clinical Model of Parkinson's

    Antiparkinsonian agents that are direct dopamine (DA) agonists, such pramipexole, have shown to be neuroprotective against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced damage to the DA...

  • Fast Track, 2002
    Study of the Metabolism and Aggregation of Alpha-synuclein in Parkin-depleted Neuronal Cells

    While only a small fraction of Parkinson's disease (PD) cases are genetic, they possess most of the common clinical and pathological features of PD, which ordinarily has no traceable cause. As this...

  • Fast Track, 2002
    Transgenic Model for Intraneuronal Oxidative Stress

    One of the major questions we have often encountered in the Parkinson's disease (PD) study is why dopamine neurons in the substantia nigra of patient brains are selectively undergone degeneration....

  • Fast Track, 2002
    High Throughput Drug Screening for Protection Against DA Neuron Degeneration

    We are utilizing a small worm called, C. elegans to develop a method to examine a large number of drugs that may protect against the type of cell death that occurs in Parkinson's disease (PD). The...

  • Fast Track, 2002
    Testosterone Therapy in Parkinson's disease

    The University of Florida Movement Disorders Center will be following up the promising results of two preliminary studies of testosterone replacement therapy in male Parkinson's disease patients in a...

  • Fast Track, 2002
    Signaling Cascades Underlying Use-dependent Neuroprotection in Parkinsonism

    Parkinson's disease is characterized by the progressive loss of nerves in the brain that produce a chemical called dopamine, which is important in the control of motor function. Current therapies...

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