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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Fast Track, 2002
    Differentiation catalysts for the production of dopaminergic neurons

    Embryonic stem (ES) cells can replicate indefinitely in an undifferentiated state and develop into all cells and tissues in the body. These unique characters of ES cells imply their application as a...

  • Fast Track, 2002
    Pre-clinical Model for Pharmacological Upregulation of Molecular Chaperones

    Lewy bodies including alpha-synuclein in substantia nigra neurons are characteristic of Parkinson's disease. These aggregates may cause the disease or may represent disease-causing protein folding...

  • Fast Track, 2002
    The role of the DJ-1 gene in early-onset recessive Parkinson's Disease (PARK7)

    Several families with rare genetic forms of Parkinson's disease have been identified, and at present mutations in three genes implicated in familial forms of parkinsonism have been described: the...

  • Cell Line, 2002
    Development of a Stem Cell Replacement Therapy for Parkinson's Disease: Induction of Midbrain DA Neurons from ES Cells

    In the present project three groups at the Karolinska Institute join forces in order to: 1) Identify molecular players capable of inducing a midbrain dopaminergic (DA) phenotype. We previously found...

  • Cell Line, 2002
    Development and Utilization of Dopaminergic Cell Lines for the Treatment of Parkinson's Disease

    We have recently succeeded in differentiating adult human and animal bone marrow stromal stem cells (BMSCs) into neurons (nerve cells). A subpopulation of the neurons activates functions that are...

  • Cell Line, 2002
    Development & characterization of adult substantia nigra derived neural progenitor cells

    There is growing evidence that certain areas of the adult central nervous system retain the capacity to generate new neurons from endogenous immature progenitor cells. Our preliminary results show...

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