The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
-
The Role of Protein Degradation in Parkinson's Disease, 2002Lentiviral Mediated Effect of Chaperones & Parkin in a Genetic Model of Parkinson's disease
The study of familial Parkinson disease indicates that the loss of nerve cells of a brain structure named the substantia nigra may be related to the accumulation of proteins aggregating within these...
-
The Role of Protein Degradation in Parkinson's Disease, 2002Regulation of Nurr1 Nuclear Receptor Transcriptional Activity by the Ubiquitin Proteasome System
Parkinson's disease (PD) is a neurodegenerative disease involving progressive and selective death of dopamine producing neurons located in the midbrain. Survival and normal activity of these neurons...
-
Cell Line, 2002Generation of Functional Dopamine Neurons of Human Origin for Grafting in Parkinson's Disease
The project will use multipotent neural stem cells as starting material. These cells, which reside in the central nervous system, will be isolated from the developing brains of five- to eight-week-old...
-
Fast Track, 2001Lentiviral Delivery of Neublastin to MPTP-Treated Pre-clinical models
Parkinson's disease (PD) results primarily from striatal dopamine (DA) insufficiency and degeneration of dopaminergic neurons within the substantia nigra pars compacta. The cause of PD still remains...
-
Fast Track, 2001Rapid Parkinson's Drug Screen Using Parkin Knockout Stem Cells
Autosomal recessive loss-of-function mutations in the parkin gene are the most common cause of familial Parkinson's disease (PD), which is characterized by selective loss of dopaminergic (DA) neurons...
-
Fast Track, 2001PET Neuroimaging Study of the Brain Serotonin Transporter in Parkinson's Disease: Relationship to Clinical Depression
Approximately 40% of patients with Parkinson's disease (PD) suffer from depression, which in many cases is more disabling than the impairment of motor function. Since the original discovery by Oleh...
Apply for a Grant
Our funding programs support basic, translational and clinical research from academia and industry.