The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Alpha-Synuclein Biology and Therapies, 2019How Does Alpha-synuclein Cause Neurodegeneration?
Study Rationale:
The protein alpha-synuclein has a central, causative role in Parkinson's disease, but we do not understand how it contributes to cell degeneration. Mutations in the gene (SNCA) that... -
Research Grant, 2019Interpretation of Accelerometer Data with Deep Learning
Study Rationale:
In-home monitoring of the severity of Parkinson's disease (PD) may help guide therapeutic decisions and prevent life-threatening falls. Deep learning is the state-of-the-art tool for... -
Research Grant, 2019Parkin-activating Small Molecules in a Model of Mitophagy
Study Rationale:
The protein parkin plays a critical role in the health and maintenance of the brain cells that make dopamine, which degenerate in Parkinson's disease. Scientific evidence shows that... -
GBA Biology and Therapies, 2019Inflammation in People with Parkinson's and a GBA Mutation and in Their Unaffected Relatives
Study Rationale:
Parkinson's is a complex disease combining genetic, environmental and inflammatory causes. Mutations in the GBA gene are a leading genetic contributor to Parkinson's disease. While... -
Biomarkers of Protein Handling/Autophagy, Exosomes and Lipid, 2019Extracellular Vesicles from Urine as Non-invasive Biomarkers
Study Rationale:
Parkinson's therapeutic development has suffered because Parkinson's symptoms develop only after significant brain degeneration has occurred, leaving significant time between disease... -
Research Grant, 2019Discovery and Development of Parkin Activators as Therapies for Parkinson’s Disease
Study Rationale:
Impaired mitochondria are a shared feature of Parkinson's disease (PD). Thus restoration of mitochondrial function offers a therapeutic avenue to slow the progression of PD. Parkin...
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Our funding programs support basic, translational and clinical research from academia and industry.