The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Rapid Response Innovation Awards, 2007Ethics of Sham Surgery Controls to Test Novel Parkinson's Disease Interventions
Objective/Rationale:
When experimental treatments involve neurosurgery, researchers often use a placebo condition called sham surgery, which involves an invasive procedure (e.g., partial thickness... -
Rapid Response Innovation Awards, 2007Re-distribution of Brain Gangliosides for Treatment of Parkinson's Disease
Project Description:
A pre-clinical model of Parkinson's disease can be generated by injecting MPTP, a toxin that results in specific damage to the same part of the brain that is damaged in Parkinson's...
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Rapid Response Innovation Awards, 2007Neuroprotective effects of isradipine in a pre-clinical model of Parkinson’s disease
Objective/Rationale:
Recent work by our group has shown that blocking L-type Ca2+ channels protects vulnerable dopaminergic neurons in three animal models Parkinson’s disease (PD). Isradipine, a high... -
Rapid Response Innovation Awards, 2007Genetic characterization of Omi/Htra2 (PARK13) in autosomal dominant and sporadic Parkinson’s disease
Objective/Rationale:
Identification of DNA variations that cause familial/sporadic parkinsonism has provided insight into the biological pathways involved in disease. Thirteen loci (PARK1-13) have... -
Target Validation, 2007Development of Lentiviral DN-TNF Vectors: A Novel Anti-inflammatory Gene Therapy to Block Nigrostriatal Degeneration
Objective/Rationale:
A growing number of epidemiological and experimental animal studies implicate neuroinflammatory mechanisms in the progressive death of midbrain dopamine (DA) neurons in Parkinson’s...
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Clinical Intervention Awards, 2007Serotonin and Sleep Disordered Breathing in Parkinson Disease
Objective/Rationale:
Sleep related problems are a major cause of impairment in Parkinson's disease. Recent studies indicate a high incidence of a disabling sleep disorder – sleep disordered breathing...
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Our funding programs support basic, translational and clinical research from academia and industry.