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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2019
    PPM1H Activators for the Treatment of Parkinson’s Disease

    Study Rationale:
    Although Parkinson’s disease (PD) causes are in most cases unknown (idiopathic) some cases are linked to a person’s genetics. Leucine-rich repeat kinase 2 (LRRK2) is a very important...

  • Epidemiological Parkinson's Risk Modifiers, 2019
    Study in Finnish Population to Identify Therapies with Repurposing Potential for Parkinson’s Disease

    Study Rationale:
    Effective treatments for slowing the progression of Parkinson’s disease are urgently needed. Searching for possible treatments among drugs already used for other indications is a...

  • Therapeutic Pipeline Program, 2019
    Biomaterial-enhanced Cellular Brain Repair for Parkinson's Disease

    Study Rationale:
    One promising approach for the treatment of Parkinson’s is to replace the cells that have died in the disease through transplantation of healthy cells into the brain. However, this...

  • Target Advancement Program, 2019
    Connexins as a New Therapeutic Target to Impede Spreading of Alpha-synuclein Pathology

    Study Rationale:
    Direct cellular connectivity has recently been implicated in the transfer of alpha-synuclein pathology associated with Parkinson’s disease. The gap junction proteins known as...

  • Research Grant, 2019
    Immune Cell Dysfunction in PINK1 Parkinson’s Models

    Promising Outcomes of Original Grant:
    In our previous project, we significantly advanced the characterization of PINK1 knockout (KO) models. We found evidence of innate and adaptive immune cell...

  • Research Grant, 2019
    Restoring the Nigrostriatal Pathway with Living Micto-tissue Engineered Axonal Tracts Supplement

    Promising Outcomes of Original Grant:
    The classic motor deficits of Parkinson’s disease (PD) are caused by degeneration of dopamine neurons, resulting in the loss of part of the neurons called axonal...

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Our funding programs support basic, translational and clinical research from academia and industry.

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