The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
-
Research Grant, 2018Searching for New Causes of LRRK2-associated Parkinson's Disease
Study Rationale:
Mutations (changes) in the LRRK2 gene are a leading genetic cause of Parkinson's disease (PD) and cause dysfunction in the LRRK2 protein. However, not all LRRK2 mutations cause the... -
Alpha-synculein Biology and Therapies, 2018Supporting Alpha-synuclein Attachment to Synaptic Vesicles for the Treatment of Parkinson's Disease
Study Rationale:
Alpha-synuclein is a sticky protein that clumps in the brains of people with Parkinson's disease (PD). Researchers believe that alpha-synuclein clumps can damage nerve cells in the... -
Research Grant, 2018Autophagy and Mitochondrial Dysfunction as Potential Therapeutic Targets in Inherited Parkinson's Disease
Study Rationale:
Mutations (changes) in the gene that controls the production of enzyme glucocerebrosidase (GCase) are the most common risk factor for inherited Parkinson's disease (PD). We have... -
Research Grant, 2018Assessing Proteins LRRK2, GCase and Cytokines in Immune Cells
Study Rationale:
Leucine-rich repeat kinase 2 (LRRK2) and glucocerebrosidase (GCase) are two proteins linked to an increased risk of developing Parkinson’s disease (PD). Both proteins are produced by... -
Research Grant, 2018Studying GBA Pseudogene as a Controller of GBA and Alpha-synuclein
Study Rationale:
Mutations (changes) in the GBA gene are the most common genetic risk factor for Parkinson’s disease (PD). GBA has a clone called pseudogene, a similar stretch of DNA that, unlike the... -
GBA Biology and Therapies, 2018Link between LRRK2 Activity and Glucocerebrosidase Deficits in Idiopathic Parkinson’s Disease
Study Rationale:
Earlier work from this group reported greater LRRK2 activity in people with idiopathic (cause unknown) Parkinson’s. This project builds on those findings to investigate how that...
Apply for a Grant
Our funding programs support basic, translational and clinical research from academia and industry.