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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Computational Science, 2017
    Using Mathematical Tools to Explain the Variability in Parkinson’s Disease Symptoms and Progression

    Study Rationale: 
    Parkinson’s disease (PD) symptoms and progression vary greatly, making each Parkinson’s experience unique. The goal of this study is to winnow out the most relevant factors...

  • LRRK2 Biology Consortium, 2017
    Describing the Structure and Function of LRRK2

    Study Rationale:
    Although leucine-rich repeat kinase 2 (LRRK2) is the greatest known genetic contributor to Parkinson's disease (PD), little is known about its structure and function. To better...

  • Research Grant, 2017
    Using Neural Cells to Test New Drugs that Activate PINK1 and Parkin

    Promising Outcomes of Original Grant:
    Even though most people with Parkinson's disease (PD) do not have a genetic mutation -- a change in their DNA -- that causes the disease, genes can influence the...

  • Research Grant, 2017
    Radioactive Molecules for Detection of Alpha-synuclein and Amyloid-beta in the Brain

    Study Rationale:
    We will develop radioactive alpha-synuclein and beta-amyloid tracers -- molecules that allow researchers and clinicians to detect these two proteins in the brain using imaging...

  • Access to Data & Biospecimens, 2017
    Klotho and Parkinson’s disease

    Study Rationale:                   

    Genetic studies have identified a powerful “aging suppressor gene”, Klotho, that may play a role in delaying age-related declines in cellular and tissue functioning...

  • Target Advancement Program, 2017
    Disruption of Pathological Protein-protein Interactions in Alpha-synuclein

    Study Rationale:
    The spread of alpha-synuclein (sticky protein that clumps in the brains of those with Parkinson's) occurs through a cell-to-cell prion-like (spreading) mechanism. Disrupting the...

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