The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Therapeutic Pipeline Program, 2014Effects on Gait and Balance of Augmenting Cholinergic Function
Study Rationale:
Impairments of gait and balance are common and life-altering in patients with Parkinson’s disease (PD). These impairments are incompletely controlled with... -
Research Grant, 2014Parkinson's Disease Biomarker Discovery and Verification Using Multiple Reaction Monitoring
Study Rationale:
Multiple candidate Parkinson’s disease (PD) biomarkers have been identified over the years, but none have been properly validated. Using a targeted mass spectrometry platform, a... -
Target Validation, 2014Targeting Internalization and Aggregation of Alpha-synuclein Proteopathic Seeds with Glycosaminoglycan Interacting Small Molecules (GISMO)
Objective/Rationale:
Evidence points to key roles for alpha-synuclein and cell-surface glycosaminoglycans (GAGs) — a type of carbohydrate molecules — in the onset of neurodegenerative... -
Access to Data and Biospecimens, 2014Analysis of Circulating Brain-Enriched microRNA as Biomarkers for Parkinson’s Disease
Study Rationale:
Early detection of neurodegenerative diseases can lead to more effective therapeutic intervention. DiamiR proposes a diagnostic approach based on analysis of... -
Research Grant, 2014Increasing Glucocerebrosidase Activity as a Therapeutic Strategy
Objective/Rationale:
Mutations in GBA1, the gene encoding the protein glucocerebrosidase, represent a common genetic risk factor for developing Parkinson disease (PD). PD patients with and... -
Therapeutic Pipeline Program, 2014Development of a mGluR4 Therapeutic for Parkinson's Disease
Study Rationale:
One of the major objectives for the development of new treatments for Parkinson’s disease is to find alternatives to the stimulation of the dopaminergic system through levodopa and...
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Our funding programs support basic, translational and clinical research from academia and industry.