The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Target Validation, 2012Validating Monoacylglycerol Lipase Inhibitors in Combatting Parkinson’s Disease
Objective/Rationale:
Chronic and persistent inflammation in the brain has been shown to be an underlying driver of Parkinson’s disease (PD). Anti-inflammatory strategies may be beneficial... -
Dyskinesia Challenge, 2012Evaluation of Cortical Resonant Oscillations as a Novel Target for Treatment of Dyskinesia
Objective/Rationale:
In our research we aim to identify changes in neuronal circuits that cause motor symptoms in Parkinson’s disease (PD) by recording neuronal activity in healthy and in... -
Dyskinesia LEAPS, 2012Topiramate as an Adjunct to Amantadine in the Treatment of Dyskinesia in Parkinson's Disease
Objective/Rationale:
Dyskinesia is a term used to describe involuntary movements that develop as side effects of dopamine drugs used to treat Parkinson's disease. Dyskinesias are frequent and... -
Research Grant, 2012The Transfer of Alpha-Synuclein: Mechanistic and Therapeutic Studies
Objective/Rationale:
This three-year collaborative project between three seasoned Parkinson’s disease (PD) investigators capitalizes on their extensive PD research experience and new understanding of... -
Alpha-synuclein Biology Challenge, 2012Alpha-synuclein Aggregation Leads to Loss of Functional Forms of the Protein and Toxicity
Objective/Rationale:
The protein alpha-synuclein has been linked to Parkinson’s disease (PD). The prevailing hypotheses state that this protein is directly toxic to neurons and thus the removal of... -
LRRK2 Challenge, 2012Characterizing Region Specific Splice Isoforms of LRRK2
Objective/Rationale:
LRRK2 is one of the most important genetic risk factors that we know about for Parkinson’s disease: Tens of thousands of people in the US have mutations in this gene...
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Our funding programs support basic, translational and clinical research from academia and industry.