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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • MJFF Research Grant, 2012
    Neuroimaging Markers Predict Cognitive Decline in PD

    Promising Outcomes of Original Grant:
    Excessive amounts of amyloid in brain tissue are believed to be toxic and cause the neuronal damage that results in dementia.  Amyloid deposits can be detected in...

  • MJFF Research Grant, 2012
    Mechanisms of Parkin Recruitment and Mitophagy

    Promising Outcomes of Original Grant:
    The protein Parkin is thought to be required for the maintenance of healthy mitochondria, critical subcellular organelles that govern cellular energy production...

  • Rapid Response Innovation Awards, 2012
    Mifunctional Cembranoids for Therapy of Parkinson’s Disease

    Objective/Rationale:
    Although considerable achievements have been made in the understanding of pathophysiology of Parkinson’s disease (PD), there are still limited effective approaches available for...

  • Dyskinesia Challenge, 2012
    The Effects of Memantine on Levodopa Induced Dyskinesias (LIDs) in MPTP-treated Pre-clinical Models

    Objective/Rationale:
    Levodopa is the mainstay of treatment for the motor symptoms of Parkinson’s disease.  Unfortunately one of the long term side effects of levodopa treatment is the development of...

  • Rapid Response Innovation Awards, 2012
    Functional Integration of Grafted Human Induced Neuronal (iN) Cells in Parkinson's Disease

    Objective/Rationale:
    Recently, genetic manipulation of human cells from various organs, e.g. skin, enabled direct generation of human nerve cells (so-called induced neurons – iNs) that potentially can...

  • Rapid Response Innovation Awards, 2012
    Trace Amines and Their Metabolites as Potential Heraldic Markers in Parkinson’s Disease

    Objective/Rationale:
    Tools for early and unambiguous diagnosis of PD are currently missing and disease symptoms are easily mistaken. On the other hand, prompt recognition of PD subjects may increase...

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Our funding programs support basic, translational and clinical research from academia and industry.

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