The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Program-non-specific Funding, 2009The Impact of Oligomerization on Alpha-Synuclein Toxicity
Objective/Rationale:
We aim to find mutants of alpha-synuclein that form oligomers but do not form fibrils to specifically test their underlying toxicity in an in vivo model. This approach will... -
MJFF Research Grant, 2009Gastrointestinal Function in Parkinson's Mice
Promising Outcomes of Original Grant:
Our original project was designed to screen several well-known models of Parkinson’s disease to determine if any mimic the gastrointestinal symptoms (constipation... -
Program-non-specific Funding, 2009Analysis of Adhesion and Chemotactic Factor Expression Possibly Involved in T Cell Brain Extravasation in Parkinsonism: Preliminary Studies for a Target Validation
Promising Outcomes of Original Grant:
In a previous study funded by The Michael J. Fox Foundation, we have provided compelling evidence that brain infiltration of peripheral immune cells (in particular... -
Target Validation, 2009Testing PDE-1 Inhibitor in MPTP-treated Macaques
Promising Outcomes of Original Grant:
Our goal is to develop novel therapeutic molecules that promote normal dopamine neurotransmission in the brain affected by PD. We hypothesize that these molecules... -
MJFF Research Grant, 2009Investigating Placebo Effects in Parkinson's Disease with Functional MRI
Objective/Rationale:
Many researchers believe that placebo treatments may have beneficial effects on symptom progression in Parkinson’s disease, but there is very little experimental evidence on... -
Critical Challenges in PD: Alpha-synuclein Neuroimaging, 2009Development and Screening of Contrast Agents for In Vivo Imaging of PD
Objective/Rationale:
This project aims to develop reagents to image alpha-synuclein pathology in the brains of living patients as a PD specific biomarker.
Project Description:
Using a library of small...
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Our funding programs support basic, translational and clinical research from academia and industry.