The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Novel Approaches to Drug Discovery for Parkinson's Disease, 2009Development of HSF1 Effectors as Parkinson's Disease Therapeutics
Objective/Rationale:
This project will focus on the development of small molecule therapeutics to treat Parkinson’s disease by advancing lead compounds that modulate protein chaperones. Protein... -
Novel Approaches to Drug Discovery, 2009Optimizing Metalloporphryins for Clinical Development
Objective/Rationale:
Oxidative stress is a well-defined therapeutic target for Parkinson’s disease (PD) and antioxidant therapy is one of the most promising neuroprotective strategies for its... -
Novel Approaches to Drug Discovery for Parkinson's Disease, 2009Optimization of Alpha-synuclein 5'UTR Directed Translation Blockers as Novel Drugs for Parkinson's Disease
Objective/Rationale:
Posiphen is a well-tolerated translation blocker of the Parkinson’s disease causative protein alpha-synuclein (SNCA) via the 5’untranslated region (5’UTR) in its mRNA. Our goal is... -
Novel Approaches to Drug Discovery for Parkinson's Disease, 2009Cerium Oxide Nanoparticles in Treatment of Parkinson's Disease
Objective/Rationale:
Nanotechnology and nanomedicine hold potential to advance medical treatment through construction of materials with enhanced biological effects, at the atomic scale. By... -
Novel Approaches to Drug Discovery for Parkinson's Disease, 2009Novel JNK Inhibitors as Therapeutic Agents for Parkinson's Disease
Objective/Rationale:
Our objective is to test the in vivo pharmacokinetic profile, mode of action and efficacy of two novel and highly selective JNK inhibitors in the MPTP (1-methyl-4-phenyl-1,2,3,6... -
Program-non-specific Funding, 2009LRRK2 Variation in Parkinson's Disease
Objective/Rationale:
Over the last decade genetic causes of Parkinson’s disease have given great insights into the pathways and mechanisms that play a role in the disease. The discovery of common...
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Our funding programs support basic, translational and clinical research from academia and industry.