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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Rapid Response Innovation Awards, 2007
    Development and Initial Characterization of an Enzyme-linked Immunosorbent Assay for the Candidate PD Risk Marker ST13

    Objective/Rationale:
    Clinical signs of Parkinson’s disease develop only after the death of around 70 percent of vulnerable dopaminergic neurons. Laboratory tests for PD are not currently available...

  • Rapid Response Innovation Awards, 2007
    Methylphenidate for the Treatment of Gait Impairment in Parkinson's Disease

    Objective/Rationale:
    The objective of this study is to explore the effects of methylphenidate on the gait of patients with Parkinson’s disease who are experiencing shuffling and freezing...

  • Rapid Response Innovation Awards, 2007
    Understanding the Molecular and Functional Changes of CB1/D2/A2A Receptor Complexes in the Hemi-parkinsonian Pre-clinical Model

    Objective/Rationale:
    Future therapies in Parkinson’s disease (PD) may derive from the existence of intramembrane heteromeric receptor complexes containing the dopamine D2 receptor. The ability of...

  • Rapid Response Innovation Awards, 2007
    A Novel Strategy for the Selection and Transplantation of Dopamine-Specified Human Embryonic Stem Cells

    In parkinson’ disease (PD), neurodegeneration is largely confined to one discrete group of nerve cells that produce the chemical dopamine (DA). Since the death of most DA neurons almost always...

  • Rapid Response Innovation Awards, 2007
    Gene-Environment Interactions in Parkinson's Disease

    Objective/Rationale:
    Although the causes of sporadic Parkinson’s disease are still unknown, recent evidence suggests that exposure to pesticides increases the risk for PD. However, most of these...

  • Rapid Response Innovation Awards, 2007
    Everyday Action Impairment in People with Parkinson's Disease Dementia/Dementia with Lewy Bodies

    Objective/Rationale:
    Parkinson’s disease (PD) and Parkinson’s Disease Dementia/Dementia with Lewy Bodies (PDD/DLB) have been associated with cognitive deficits and everyday action impairment (EAI; e.g...

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