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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Rapid Response Innovation Awards, 2007
    Feasibility of Intranasal Delivery of GDNF for Parkinson's Disease

    Objective/Rationale:
    Glial cell line-derived neurotrophic factor (GDNF) is a small protein that potently promotes the survival of many types of neurons. The therapeutic potential of GDNF for Parkinson...

  • Rapid Response Innovation Awards, 2007
    Virtual Reality to Reduce Fall Risk in Patients with Parkinson’s Disease

    Objective/Rationale:
    Virtual Reality (VR) allows for training in complex environments, while motivating subjects to perform numerous repetitions of the training tasks under well-controlled conditions...

  • LEAPS, 2007
    Discovery of mGluR4 Potentiators for Symptoms & Side Effects and Disease-Modifying Treatment of PD

    Objective/Rationale: 
    Surgical approaches to treatment of Parkinson’s disease using deep brain stimulation and corrective lesions provide valuable insights into novel approaches for treatment of this...

  • Biomarkers, 2007
    A Gene Expression Signature for the Early Detection of Parkinson Disease

    Objective/Rationale:
    The primary goal for the project is to develop a highly accurate and reproducible gene expression signature in blood to discriminate Parkinson disease both from other closely...

  • Biomarkers, 2007
    Validation of CSF Alpha-synuclein as a Biomarker for Parkinson's disease

    Objective/Rationale:
    Accumulation of alpha-synuclein within certain nerve cells represents one of the hallmarks of classical Parkinson disease. Our team recently discovered that alpha-synuclein levels...

  • Biomarkers, 2007
    Multimodal MRI Markers for Parkinson's Disease

    Objective/Rationale:
    The assessment of Parkinson’s disease is currently based on clinical symptoms that make an accurate diagnosis challenging, especially early on, when subtle impairment of movement...

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