Funded Studies

Study Rationale: Sterols, including cholesterol, are very abundant in the brain, where they form important components of cell membranes and act as signaling molecules within and between cells...

Study Rationale: Levodopa (L-dopa) is the primary medication used to treat Parkinson’s disease (PD). For L-dopa to exert its effect, it must enter the brain and be converted to the chemical dopamine...

Study Rationale: Although new treatments are being developed to slow the progression of Parkinson’s disease (PD), assessing their effectiveness remains a challenge. Standard evaluations, conducted in...

Study Rationale: Studies show that the intestinal environment can affect the activity of the nervous system, and inflammation in the gut could contribute to the brain changes associated with Parkinson...

Study Rationale: Parkinson’s disease (PD) is characterized by the buildup of misfolded forms of alpha-synuclein. A vaccine designed to target this abnormal protein has demonstrated safety...

Study Rationale: Persistent activation of the immune cells that reside in the brain leads to a state of chronic inflammation that contributes to the degeneration of neurons in Parkinson’s disease (PD)...