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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Specification, Patterning, and Maintenance of Midbrain Dopam, 2006
    Generation of Midbrain Dopamine Neurons from Human ES Cells by Forced Expression of Lmx1a

    Drs. Ericson and Perlmann have identified two key transcription factors (Lmx1a and Msx1) that regulate early development of dopamine neurons and can induce nearly 90% ‘authentic’ dopamine neurons when...

  • Clinical Discovery Awards, 2006
    Preventing falls and improving mobility in people with Parkinson's disease

    Falls are common and disabling in people with Parkinson's disease, affecting up to 60% of those who live at home. This clinical research trial aims to minimize the number of falls and fall-related...

  • Clinical Discovery Awards, 2006
    Workplace Exposures and Biomarkers of Parkinsonism in Welders

    The etiology of Parkinson's disease is unknown although previous research has implicated environmental factors in most cases. We have previously shown that welding, an occupation performed by over 500...

  • Clinical Discovery Awards, 2006
    Treating speech disorders in patients with Parkinson's disease using altered auditory feedback

    Speech problems are common in patients with Parkinson's disease. At an early stage, patients may find it hard to project their voice. As the disease progresses, patients start to have difficulty...

  • Dopamine-Non-Responsive Symptoms of Parkinson's Disease, 2006
    The ReStore Study

    Apathy is a syndrome characterized by a primary lack of motivation and is manifested as a lack of effort and productivity, dependence on others for structuring daily activities, loss of interest in...

  • Dopamine-Non-Responsive Symptoms of Parkinson's Disease, 2006
    Development of a Model of Postural Disturbance by Lesioning Non-cholinergic Neurons

    Mounting evidence suggests that a small structure at the bottom of the brain called pedunculopontine nucleus is involved in the development of gait failure and postural instability in PD. We propose...

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