The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Community Fast Track, 2006D3 Receptor Selective Drugs for Parkinson's Dyskinesia
Biomedical research has defined two categories of dopamine receptors, the D1-like (D1 and D5 receptor subtypes) and D2-like (D2, D3 and D4 receptor subtypes) receptors. Despite the similarities in the...
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Community Fast Track, 2006T Cell Mediated Neuroprotection by Therapeutic Vaccination for Parkinson's Disease
Parkinson's disease is a progressive neurodegenerative disorder whereby the neurons of the brain that control movement die. Although the events that initiate the death of those neurons remain unknown...
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Community Fast Track, 2006AAV-Based Approach for Regulatable and Cell Type-Specific Gene Therapy in PD: Restoring Excitability to an Intrinsically Silenced Subpopulation of GP Neurons
Abnormally synchronized activity within the basal ganglia, specifically between the external globus pallidus (GPe) and subthalamic nucleus (STN), is a hallmark of altered network activity in Parkinson...
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Community Fast Track, 2006Intravenous GDNF Gene Therapy of Experimental Parkinson's Disease
Parkinson's disease is caused by the loss of cells in the brain that produce a chemical called dopamine, which is also called a monoamine. The loss of these cells has been delayed in pre-clinical...
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Community Fast Track, 2006Molecular Regulators of Dopamine Synthesis
The death of certain brain cells known as nigrostriatal neurons, which produce the neurochemical known as dopamine, ultimately causes movement dysfunction and reduced quality of life for individuals...
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Community Fast Track, 2006Establishing a role of Nurr1 in adult DA neurons by conditional gene ablation in the adult substantia nigra
We will investigate the function of the protein Nurr1 in the adult mouse brain. Nurr1 belongs to the family of steroid hormone receptors but lacks an identified ligand. We have previously shown that...
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Our funding programs support basic, translational and clinical research from academia and industry.