The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Target Validation, 2006Estrogenic Neuroprotection and the Parkinson's Disease Phenotype
Epidemiological and clinical studies have demonstrated that the prevalence of Parkinson's disease is 1.3 - 3.7 times greater in men than women. In support of this, several studies have also shown that...
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Target Validation, 2006Lowering Alpha-synuclein In Vivo: A Biological Target for PD Treatment
The goal of the proposed work is to pursue efforts in drug development for Parkinson's disease that are aimed at the underlying cause. The recent discoveries of individual genes that are linked to the...
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Target Validation, 2006Development of Novel Phosphodiesterase Inhibitors for the Symptoms & Side Effects Treatment of Parkinson's Disease
The progressive death of brain neurons containing the neurochemical dopamine is the hallmark of Parkinson's disease. The symptoms of PD can be improved by levodopa, a drug which transiently restores...
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Clinical Discovery Awards, 2006The oscillation of basal ganglia
Parkinson's disease (PD) is related to abnormal functioning of an area of the brain known as the basal ganglia. A model of how the basal ganglia works, known as the rate model, proposed about 15 years...
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Clinical Discovery Awards, 2006Parkinson Disease in the Ohio Amish
Genes play a significant role in the risk of developing Parkinson's disease. Some genes have already been identified, but several others remain to be identified. One way to find these genes is to...
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Clinical Discovery Awards, 2006Alleviating late motor complications of Parkinson's disease by a continuous dopaminergic treatment with transdermal delivery of L-DOPA Pro-drug
NeuroDerm Ltd. is developing a novel delivery system of levodopa for the treatment of Parkinson's disease. Levodopa, a well-established medication for the treatment of Parkinson's disease (PD), is...
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Our funding programs support basic, translational and clinical research from academia and industry.