The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Clinical Discovery Awards, 2006The physiological mechanisms and treatment of fatigue in PD - a longitudinal study
Fatigue is a common problem in Parkinson's and many patients continue to be bothered by fatigue despite that they are taking medications to control their motor symptoms. Transcranial magnetic...
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Target Validation, 2006Identification of therapeutics that protect against toxins and genes implicated in Parkinson’s disease via the Forkhead-mediated transcription pathway
Loss of dopaminergic neurons is one of the cardinal features of Parkinson’s disease. Medications that can delay or prevent dopaminergic loss could be beneficial in treating PD, but the optimal...
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Community Fast Track, 2005Specific Inhibition of Nucleation of Alpha-synuclein Aggregation as a Therapeutic Strategy
There is considerable evidence that aggregates of the human brain protein alpha-synuclein are a primary cause of the loss of neurons in Parkinson's disease. We have tried to find out what initiates...
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Community Fast Track, 2005Use of NR2D-selective NMDA Receptor Modulators in the Treatment of PD
The frontline pharmacological treatment for Parkinson’s disease is associated with serious side effects, creating a need for new therapeutic strategies. Recent evidence suggests that selective...
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Target Validation, 2005Testing of small molecules in an alpha-synuclein pre-clinical model of Parkinson’s disease
Although Parkinson’s disease is mainly sporadic, at least six genes have been recently linked to familial PD. It is believed that a molecular understanding of the consequences of these gene mutations...
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Target Validation, 2005In vivo Target Validation: RNA Interference to Silence Alpha-Synuclein in Parkinson’s Disease Pre-clinical Models
Recent studies have shown that a protein known as alpha-synuclein plays a central role in the development of Parkinson’s disease. While its normal function in the brain remains unknown, the...
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Our funding programs support basic, translational and clinical research from academia and industry.