The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Community Fast Track, 2004Dopaminergic Neurogenesis: From Development to Stem Cell Replacement Therapies
Parkinson's disease is a devastating neurodegenerative disorder characterized by the loss of dopamine producing neurons (dopaminergic neurons) in a specific brain region, the ventral midbrain. The...
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Community Fast Track, 2004A DJ-1 mutant zebrafish model of Parkinson’s disease (PD)
Genetic research has provided new insight into the underlying causes of Parkinson's disease, but this has not yet resulted in any direct benefit to the patients. In particular, this has not lead to...
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Community Fast Track, 2004Role of the Ras/ERK signaling pathway in the development of dyskinesia and motor fluctuationsduring chronic L-DOPA treatment
L-DOPA is the most effective treatment for Parkinson's disease, but causes adverse motor effects that limit its utility. Such effects include, abnormal involuntary movements (dyskinesia) and...
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Community Fast Track, 2004PINK1 Structure & Function
A recent discovery by our laboratory and others has revealed a new gene that is linked to several families with hereditary Parkinson Disease. This gene codes for the PTEN Induced Kinase-1 (or PINK1)...
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Community Fast Track, 2004Finding genetic risk factors for Parkinson’s disease in genetically isolated populations
What causes Parkinson's disease is largely unknown but both environmental factors and genetic risk factors play a role. Over the years researchers have identified mutations in genes that are...
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Community Fast Track, 2004Mechanisms of HIPK2-dependent Survival & Differentiation of Midbrain Dopaminergic Neurons - a Chemical Genetic Target for Parkinson's Disease
Regulation of gene expression is critical for neuronal development, survival, differentiation, and axon/dendritic arborization. While several transcription factors have been shown to be important for...
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Our funding programs support basic, translational and clinical research from academia and industry.